ReviewClinical endocrinology2011
PCOS Forum: research in polycystic ovary syndrome today and tomorrow.
Review in Clinical endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 185 citations in OpenAlex.
- Pooled it
- Genetic variants associated with insulin signaling and glucose homeostasis in the pathogenesis of insulin resistance in polycystic ovary syndrome: a systematic review.Journal of assisted reproduction and genetics · 2013 · on this mapPooled it
- FAAH as a Molecular Regulator of Endocannabinoid Signaling: Mechanistic Insights into Reproductive, Metabolic, and Inflammatory Dysfunctions in Polycystic Ovary Syndrome.Molecules (Basel, Switzerland) · 2026Review
- Hyperandrogenism triggers mtDNA release to participate in ovarian inflammation via mPTP/cGAS/STING in PCOS.iScience · 2025Article
- Alterations of cardiometabolic risk profile in polycystic ovary syndrome: 13 years follow-up in an unselected population.Journal of endocrinological investigation · 2024Article
- The Potential Utility of Tirzepatide for the Management of Polycystic Ovary Syndrome.Journal of clinical medicine · 2023Review
- Inflammatory Responses of Women with Polycystic Ovary SyndromeInternational journal of molecular and cellular medicine · 2023Article
- Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis.Frontiers in endocrinology · 2023Article
- Review
- AssociationMolecular syndromology · 2022Article
- Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-Induced Polycystic Ovarian Syndrome With Insulin Resistance.Frontiers in endocrinology · 2021Article
- Evaluation of lipid ratios and triglyceride-glucose index as risk markers of insulin resistance in Iranian polycystic ovary syndrome women.Lipids in health and disease · 2020Article
- Developmental programming: prenatal testosterone-induced epigenetic modulation and its effect on gene expression in sheep ovary†.Biology of reproduction · 2020Article
- Risk of Polycystic Ovary Syndrome in Women Exposed to Fine Air Pollutants and Acidic Gases: A Nationwide Cohort Analysis.International journal of environmental research and public health · 2019Article
- In rats with estradiol valerate-induced polycystic ovary syndrome, the acute blockade of ovarian β-adrenoreceptors improve ovulation.Reproductive biology and endocrinology : RB&E · 2019Article
- Women and Autism Spectrum Disorder: Diagnosis and Implications for Treatment of Adolescents and Adults.Current psychiatry reports · 2019Review
- Contemporary approaches to the management of polycystic ovary syndrome.Therapeutic advances in endocrinology and metabolism · 2018Review
- Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2018Article
- Effect of chamomile capsule on lipid- and hormonal-related parameters among women of reproductive age with polycystic ovary syndrome.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
- The relationship between the CYP19 alleles rs727479A/C, rs700518A/G, and rs700519C/T and pregnancy outcome after assisted reproductive technology in patients with polycystic ovary syndrome in a Chinese population: A population-based study.The Kaohsiung journal of medical sciences · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 12 institutions in 9 countries.
Funding
Abstract
objectiveTo summarize promising areas of investigation into polycystic ovary syndrome (PCOS) and to stimulate further research in this area.
designSummary of a conference held by international researchers in the field of polycystic ovary syndrome.
resultsPotential areas of further research activity include the analysis of predisposing conditions that increase the risk of PCOS, particularly genetic background and environmental factors, such as endocrine disruptors and lifestyle. The concept that androgen excess may contribute to insulin resistance needs to be re-examined from a developmental perspective, since animal studies have supported the hypothesis that early exposure to modest androgen excess is associated with insulin resistance. Defining alterations of steroidogenesis in PCOS should quantify ovarian, adrenal and extraglandular contribution, as well as clearly define blood reference levels by some universal standard. Intraovarian regulation of follicle development and mechanisms of follicle arrest should be further elucidated. Finally, PCOS status is expected to have long-term consequences in women, specifically the development of type 2 diabetes, cardiovascular diseases and hormone dependent cancers. Identifying susceptible individuals through genomic and proteomic approaches would help to individualize therapy and prevention.
conclusionsThere are several intriguing areas for future research in PCOS. A potential limitation of our review is that we focused selectively on areas we viewed as the most controversial.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.