Evidence map›Paper›PMID 21158284›Full record

ArticleMedical physics2010

Exploring the potential of context-sensitive CADe in screening mammography.

Georgia D Tourassi, Maciej A Mazurowski, Brian P Harrawood, Elizabeth A Krupinski

Abstract read
In one paragraph

Article in Medical physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Probabilistic method for context-sensitive detection of polyps in CT colonography.Proceedings of SPIE--the International Society for Optical Engineering · 2011
    Article
  10. Investigating the link between radiologists' gaze, diagnostic decision, and image content.Journal of the American Medical Informatics Association : JAMIA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Georgia D TourassiDepartment of Radiology, Carl E. Ravin Advanced Imaging Laboratories, Duke University Medical Center, Durham, North Carolina 27705, USA. georgia.tourassi@duke.edu
Maciej A Mazurowski
Brian P Harrawood
Elizabeth A Krupinski

Funding

Information-Theoretic Based CAD in MammographyR56CA101911 · NCI · DUKE UNIVERSITY · PI TOURASSI, GEORGIA · 2009 to 2009
$241k
NCI NIH HHS R56 CA101911
6 · The paper itself

Abstract

purposeConventional computer-assisted detection (CADe) systems in screening mammography provide the same decision support to all users. The aim of this study was to investigate the potential of a context-sensitive CADe system which provides decision support guided by each user's focus of attention during visual search and reporting patterns for a specific case.

methodsAn observer study for the detection of malignant masses in screening mammograms was conducted in which six radiologists evaluated 20 mammograms while wearing an eye-tracking device. Eye-position data and diagnostic decisions were collected for each radiologist and case they reviewed. These cases were subsequently analyzed with an in-house knowledge-based CADe system using two different modes: Conventional mode with a globally fixed decision threshold and context-sensitive mode with a location-variable decision threshold based on the radiologists' eye dwelling data and reporting information.

resultsThe CADe system operating in conventional mode had 85.7% per-image malignant mass sensitivity at 3.15 false positives per image (FPsI). The same system operating in context-sensitive mode provided personalized decision support at 85.7%-100% sensitivity and 0.35-0.40 FPsI to all six radiologists. Furthermore, context-sensitive CADe system could improve the radiologists' sensitivity and reduce their performance gap more effectively than conventional CADe.

conclusionsContext-sensitive CADe support shows promise in delineating and reducing the radiologists' perceptual and cognitive errors in the diagnostic interpretation of screening mammograms more effectively than conventional CADe.

Indexed as

Breast NeoplasmsCognitionDecision MakingDecision Support TechniquesDiagnosis, Computer-AssistedDiagnostic ErrorsFalse Positive ReactionsFemaleHumansMammographyObserver VariationPerceptionRadiologyReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21158284
PMCPMC2973989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.