ArticleThe Biochemical journal1990
The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding.
Article in The Biochemical journal, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed, 139 citations in OpenAlex.
- Tau Axonal Sorting and Interaction With Synaptic Plasticity Modulators Is Domain- and Isoform-Dependent in Human iPSC-Derived Neurons.Aging cell · 2025Article
- Tau; One Protein, So Many Diseases.Biology · 2023Review
- Mitochondrial Dysfunction in Rabies Virus-Infected Human and Canine Brains.Neurochemical research · 2022Article
- Microtubule-associated protein tau in murine kidney: role in podocyte architecture.Cellular and molecular life sciences : CMLS · 2022Article
- More than a marker: potential pathogenic functions of MAP2.Frontiers in molecular neuroscience · 2022Article
- Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery Is the Core.International journal of molecular sciences · 2020Review
- Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau.Frontiers in neurology · 2020Review
- Tau is required for the function of extrasynaptic NMDA receptors.Scientific reports · 2019Article
- Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration.Viruses · 2019Review
- Article
- The Evolution of Tau Phosphorylation and Interactions.Frontiers in aging neuroscience · 2019Article
- Recent Insights on Alzheimer's Disease Originating from Yeast Models.International journal of molecular sciences · 2018Review
- Our Working Point of View of Tau Protein.Journal of Alzheimer's disease : JAD · 2018Review
- Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau.Nature communications · 2017Article
- Magnetic Force-Driven Graphene Patterns to Direct Synaptogenesis of Human Neuronal Cells.Materials (Basel, Switzerland) · 2017Article
- Roles of tau protein in health and disease.Acta neuropathologica · 2017Review
- Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.BioEssays : news and reviews in molecular, cellular and developmental biology · 2017Review
- Dephosphorylation of MAP2D enhances its binding to vimentin in preovulatory ovarian granulosa cells.Journal of cell science · 2016Article
- Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.Molecular neurodegeneration · 2016Article
- Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interaction of actin with a synthetic peptide which corresponds to one of the repeated tubulin-binding sites present in tau and MAP-2 (microtubule-associated protein 2) proteins has been analysed. The analysis, which uses affinity chromatography of G-actin on a column containing the synthetic peptide, and the co-sedimentation and co-localization of F-actin and the peptide (as determined by immunoelectron microscopy), indicates that the part of the amino acid sequence of tau involved in the binding of tubulin is also involved in actin binding.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.