Evidence map›Paper›PMID 21156747›Full record

Trial reportBMJ (Clinical research ed.)2010

Effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a Swiss cheese fondue: randomised controlled crossover trial.

Henriette Heinrich, Oliver Goetze, Dieter Menne, Peter X Iten, Heiko Fruehauf, Stephan R Vavricka, Werner Schwizer, Michael Fried, Mark Fox

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00943696 (Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00943696 phase4completednot on this map

Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers

TypeinterventionalSponsorUniversity of ZurichRan2009 to 2009Enrolled12ConditionsHealthy ParticipantsArmsIngestion of white wine vs. tea during and an alco
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
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  3. Debunking health myths on the internet: the persuasive effect of (visual) online communication.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Article
  4. From bench to bar side: Evaluating theOpen life sciences · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Bitters: Time for a New Paradigm.Evidence-based complementary and alternative medicine : eCAM · 2015
    Review
  9. Tibetan herbal formula Padma Digestin modulates gastrointestinal motility in vitro.World journal of gastrointestinal pharmacology and therapeutics · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Henriette HeinrichDivision of Gastroenterology and Hepatology, University Hospital Zurich, Switzerland.
Oliver Goetze
Dieter Menne
Peter X Iten
Heiko Fruehauf
Stephan R Vavricka
Werner Schwizer
Michael Fried
Mark Fox
University Hospital of Zurich · CHUniversity of Zurich · CHSwiss Integrative Center for Human Health · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effects of drinking white wine or black tea with Swiss cheese fondue followed by a shot of cherry schnapps on gastric emptying, appetite, and abdominal symptoms.

designRandomised controlled crossover study.

participants20 healthy adults (14 men) aged 23-58.

interventionsCheese fondue (3260 kJ, 32% fat) labelled with 150 mg sodium (13)Carbon-octanoate was consumed with 300 ml of white wine (13%, 40 g alcohol) or black tea in randomised order, followed by 20 ml schnapps (40%, 8 g alcohol) or water in randomised order.

main outcome measuresCumulative percentage dose of (13)C substrate recovered over four hours (higher values indicate faster gastric emptying) and appetite and dyspeptic symptoms (visual analogue scales).

resultsGastric emptying was significantly faster when fondue was consumed with tea or water than with wine or schnapps (cumulative percentage dose of (13)C recovered 18.1%, 95% confidence interval 15.2% to 20.9% v 7.4%, 4.6% to 10.3%; P<0.001). An inverse dose-response relation between alcohol intake and gastric emptying was evident. Appetite was similar with consumption of wine or tea (difference 0.11, -0.12 to 0.34; P=0.35), but reduced if both wine and schnapps were consumed (difference -0.40, -0.01 to -0.79; P<0.046). No difference in dyspeptic symptoms was present.

conclusionsGastric emptying after a Swiss cheese fondue is noticeably slower and appetite suppressed if consumed with higher doses of alcohol. This effect was not associated with dyspeptic symptoms.

trial registrationClinicalTrials.gov NCT00943696.

Indexed as

AdultAlcohol DrinkingAlcoholic BeveragesAppetiteBreath TestsCheeseCross-Over StudiesDyspepsiaFemaleGastric EmptyingHumansMaleMiddle AgedTeaWineYoung AdultTea

Identifiers

PMID21156747
PMCPMC3272707
OpenAlexW2153443042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.