ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2012
Comparison of proton magnetic resonance spectroscopy with fluorine-18 2-fluoro-deoxyglucose positron emission tomography for assessment of brain tumor progression.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- MRI combined with PET-CT of different tracers to improve the accuracy of glioma diagnosis: a systematic review and meta-analysis.Neurosurgical review · 2019Pooled it
- The role of imaging in the management of adults with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.Journal of neuro-oncology · 2015Guideline
- Glioma surveillance imaging: current strategies, shortcomings, challenges and outlook.BJR open · 2020Review
- IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein-specific PET/CT.European journal of nuclear medicine and molecular imaging · 2019Article
- Magnetic resonance spectroscopy - Revisiting the biochemical and molecular milieu of brain tumors.BBA clinical · 2016Review
- Diagnostic and prognostic value of 18F-DOPA PET and 1H-MR spectroscopy in pediatric supratentorial infiltrative gliomas: a comparative study.Neuro-oncology · 2015Article
- Integrated PET/MRI for planning navigated biopsies in pediatric brain tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Molecular and metabolic pattern classification for detection of brain glioma progression.European journal of radiology · 2014Article
- Grading of cerebral glioma with multiparametric MR imaging and 18F-FDG-PET: concordance and accuracy.European radiology · 2014Article
- Malignant gliomas: current perspectives in diagnosis, treatment, and early response assessment using advanced quantitative imaging methods.Cancer management and research · 2014Review
- Functional imaging in adult and paediatric brain tumours.Nature reviews. Clinical oncology · 2012Review
- Brain tumors.Seminars in nuclear medicine · 2012Review
- Molecular imaging of pediatric brain tumors: comparison of tumor metabolism using ¹⁸F-FDG-PET and MRSI.Journal of neuro-oncology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectivesWe investigated the accuracy of high-field proton magnetic resonance spectroscopy ((1) H MRS) and fluorine-18 2-fluoro-deoxyglucose positron emission tomography ((18) F-FDG-PET) for diagnosis of glioma progression following tumor resection, stereotactic radiation, and chemotherapy.
methodsTwelve post-therapy patients with histology proven gliomas (six grade II and six grade III) presented with magnetic resonance imaging (MRI) and clinical symptoms suggestive but not conclusive of progression were entered into the study. (1) H MRS data were acquired and 3-dimensional volumetric maps of choline (Cho) over creatine (Cr) were generated. Intensity of (18) F-FDG uptake was evaluated on a semiquantitative scale.
resultsThe accuracy of (1) H MRS and (18) F-FDG-PET imaging for diagnosis of glioma progression was 75% and 83%, respectively. Classifying the tumors by grade improved accuracy of (18) F-FDG-PET to 100% in high-grade gliomas and accuracy of (1) H MRS to 80% in low-grade tumors. Spearman's analysis demonstrated a trend between (18) F-FDG uptake and tumor grading (ρ= .612, P-value = .272). The results of (18) F-FDG-PET and (1) H MRS were concordant in 75% (9/12) of cases.
conclusionThe combination of (1) H MRS data and (18) F-FDG-PET imaging can enhance detection of glioma progression. (1) H MRS imaging was more accurate in low-grade gliomas and (18) F-FDG-PET provided better accuracy in high-grade gliomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.