Evidence map›Paper›PMID 21154912›Full record

ReviewDevelopmental neurobiology2011

Cholecystokinin: a multi-functional molecular switch of neuronal circuits.

Soo Yeun Lee, Ivan Soltesz

Abstract readReview
In one paragraph

Review in Developmental neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 84 citations in OpenAlex.

  1. Impact of Verbal Suggestions on Finger Flexor Activation and Strength in Healthy Individuals.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Trial
  2. Article
  3. Cholecystokinin Induces CaThe European journal of neuroscience · 2026
    Article
  4. Nutrients · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Structure and function of neocortical layer 6b.Frontiers in cellular neuroscience · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Soo Yeun LeeDepartment of Anatomy and Neurobiology, University of California, Irvine, California, USA. leesyn@uci.edu
Ivan Soltesz
University of California, Irvine · US

Funding

LIMBIC EXCITABILITY AFTER FEBRILE SEIZURESR01NS038580 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SOLTESZ, IVAN · 1999 to 2010
$2.9M
NINDS NIH HHS NS38580NINDS NIH HHS R01 NS038580
6 · The paper itself

Abstract

Cholecystokinin (CCK), a peptide originally discovered in the gastrointestinal tract, is one of the most abundant and widely distributed neuropeptides in the brain. In spite of its abundance, recent data indicate that CCK modulates intrinsic neuronal excitability and synaptic transmission in a surprisingly cell-type specific manner, acting as a key molecular switch to regulate the functional output of neuronal circuits. The central importance of CCK in neuronal networks is also reflected in its involvement in a variety of neuropsychiatric and neurological disorders including panic attacks and epilepsy.

Indexed as

Molecular Dynamics SimulationAnimalsBrainCholecystokininFearHumansInterneuronsNerve NetNeural PathwaysNeuronsCholecystokinin

Identifiers

PMID21154912
PMCPMC3005241
OpenAlexW2038656764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.