ArticleVirus genes2011
Characterization of indels in poxvirus genomes.
Article in Virus genes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Patterns of genomic deletions in monkeypox virus during the 2022 outbreak in the United States.Nature communications · 2025Article
- Orthopoxvirus Genome Sequencing, Assembly, and Analysis.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus.Frontiers in immunology · 2024Article
- High-resolution mapping reveals the mechanism and contribution of genome insertions and deletions to RNA virus evolution.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Molecular detection of monkeypox and related viruses: challenges and opportunities.Virus genes · 2023Review
- Review
- Genomic annotation and molecular evolution of monkeypox virus outbreak in 2022.Journal of medical virology · 2023Article
- Recombination shapes the 2022 monkeypox (mpox) outbreak.Med (New York, N.Y.) · 2022Article
- Genomic Sequencing and Phylogenomics of Cowpox Virus.Viruses · 2022Article
- Poxvirus Recombination.Pathogens (Basel, Switzerland) · 2022Review
- Genomic Sequencing and Analysis of a Novel Human Cowpox Virus With Mosaic Sequences From North America and Old World Orthopoxvirus.Frontiers in microbiology · 2022Article
- Review
- Article
- A poxvirus pseudokinase represses viral DNA replication via a pathway antagonized by its paralog kinase.PLoS pathogens · 2019Article
- Article
- Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol.The Journal of general virology · 2018Article
- Article
- Article
- Competitive outcome of multiple infections in a behavior-manipulating virus/wasp interaction.Ecology and evolution · 2015Article
- Evolution of and evolutionary relationships between extant vaccinia virus strains.Journal of virology · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By comparing sets of variola virus (VARV) genomes and sets of vaccinia virus (VACV) genomes, it was found that the insertion and deletion of small pieces of DNA (3-25 nucleotides) were common events among these poxviruses. Insertion events were characterized by the creation of tandem direct repeats, whereas the deletion events generally took place between two direct repeats that were separated by a few nucleotides. A number of the VARV and VACV indels clearly did not fit the expected phylogenetic tree patterns. Some of these were found to be the result of coincident events, but others, in VACV, suggest recombination among the VACV genomes. Such recombination would make the construction of phylogenetic trees problematic. The growth of VACV under artificial conditions and at high multiplicities does not select against these deletions.
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