ArticleWorld journal of surgery2011
Preoperative vitamin D deficiency predicts postoperative hypocalcemia after total thyroidectomy.
Article in World journal of surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Definition and diagnosis of postsurgical hypoparathyroidism after thyroid surgery: meta-analysis.BJS open · 2022Pooled it
- Huge variations in definition and reported incidence of postsurgical hypoparathyroidism: a systematic review.Endocrine · 2019Pooled it
- Impact of Preoperative Calcium and Magnesium Supplementation on Quality of Life and Hypocalcemia Post-Thyroidectomy.Endocrinology, diabetes & metabolism · 2026Trial
- Short-Term Hypocalcemia Prophylaxis With Calcitriol Before Thyroidectomy.Deutsches Arzteblatt international · 2021Trial
- Trial
- Does preoperative 25-hydroxyvitamin D status significantly affect the calcium kinetics after total thyroidectomy?World journal of surgery · 2013Trial
- Combining early postoperative parathyroid hormone and serum calcium levels allows for an efficacious selective post-thyroidectomy supplementation treatment.World journal of surgery · 2012Trial
- The BMI impact on thyroidectomy-related morbidity; a case-matched single institutional analysis.BMC surgery · 2025Observational
- Article
- Preoperative calcium and vitamin D supplementation may reduce postoperative hypocalcaemia after total thyroidectomy.Archives of medical science : AMS · 2025Article
- The effect of preoperative vitamin D values on hypocalcemia after total thyroidectomy.Turkish journal of surgery · 2024Article
- The Impact of Thyroid Surgery on Calcium and Magnesium Homeostasis: A Prospective Study.Cureus · 2024Article
- Preoperative Vitamin.D Status and Post-Total Thyroidectomy Hypocalcemia.Iranian journal of otorhinolaryngology · 2024Article
- Does Vitamin D Deficiency Really Increase the Risk of Post-surgical Hypoparathyroidism?Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Risk Factors for Calcium-Phosphate Disorders after Thyroid Surgery.Biomedicines · 2023Article
- Preoperative vitamin D level is significantly associated with hypocalcemia after total thyroidectomy.BMC musculoskeletal disorders · 2022Article
- Vitamin D Deficiency Reduces Postthyroidectomy Protracted Hypoparathyroidism Risk. Is Gland Preconditioning Possible?Journal of the Endocrine Society · 2022Article
- [Review of clinical practice guidelines for hypoparathyroidism].Problemy endokrinologii · 2021Review
- Preoperative vitamin D deficiency is associated with increased risk of postoperative hypocalcemia after total thyroidectomy.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- Post-Operative Permanent Hypoparathyroidism and Preoperative Vitamin D Prophylaxis.Journal of clinical medicine · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransient postthyroidectomy hypocalcemia occurs in up to 30% of patients. We evaluated the effect of vitamin D deficiency on postthyroidectomy hypocalcemia.
methodsData were collected prospectively between January 2006 and March 2009. A total of 166 consecutive total thyroidectomies were analyzed regarding the relation between preoperative vitamin D3 levels and postoperative corrected calcium levels. Patients were divided into three groups dependent upon the preoperative vitamin D3 level: group 1, <25 nmol/l; group 2, 25-50 nmol/l; group 3, >50 nmol/l (conversion factor of 2.5× between nanomoles per liter and nanograms per milliliter). Hypocalcemia was defined as a postoperative calcium level<2.00 mmol/l (8 mg/dl). Hospital length of stay was recorded.
resultsThere was a difference in postoperative hypocalcemia between the three vitamin D3 groups (group 1 (32%) vs. group 2 (24%) vs. group 3 (13%). Hypocalcemia in group 1 (vit D<25 nmol/l, <10 ng/ml) was significantly more likely than in group 3 (vit D>50 nmol/l, >20 ng/ml) (P=0.025, χ2 test. Vitamin D3 deficiency was also associated with a longer hospital stay (median stay 2 days vs. 1 day, P<0.001, Wilcoxon rank test).
conclusionsThere is a significant difference in postoperative hypocalcemia rates between those with vitamin D levels>50 nmol/l (>20 ng/ml) and those with a level of <25 nmol/l (<10 ng/ml). Vitamin D deficiency leads to a delay in discharge owing to a higher likelihood of hypocalcemia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.