Evidence map›Paper›PMID 21153366›Full record

ArticleAdvances in experimental medicine and biology2011

The extracellular matrix protein CCN1 dictates TNFα and FasL cytotoxicity in vivo.

Chih-Chiun Chen, Vladislava Juric, Lester F Lau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. CCN1/CYR61: the very model of a modern matricellular protein.Cellular and molecular life sciences : CMLS · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chih-Chiun ChenDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago College of Medicine, 900 S. Ashland Avenue, Chicago, IL 60607, USA.
Vladislava Juric
Lester F Lau

Funding

Regulation of TNF-alpha by Integrin-Mediated Matrix SignalingR01GM078492 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2007 to 2018
$4.3M
The Matricellular Protein CCN1 in Wound HealingR01AR061791 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2011 to 2021
$3.8M
Structure and Function of the Matricellular Protein CCN1R01CA046565 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 1988 to 2008
$3.0M
Integrin-Matrix Interaction in Cardiovascular DevelopmentR01HL081390 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2007 to 2010
$1.6M
NCI NIH HHS CA46565NCI NIH HHS R01 CA046565NHLBI NIH HHS HL81390NHLBI NIH HHS R01 HL081390NIAMS NIH HHS R01 AR061791NIGMS NIH HHS GM78492NIGMS NIH HHS R01 GM078492
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisAnimalsCysteine-Rich Protein 61Extracellular MatrixFas Ligand ProteinHumansMiceModels, BiologicalReactive Oxygen SpeciesSignal TransductionTumor Necrosis Factor-alphaCysteine-Rich Protein 61Fas Ligand ProteinReactive Oxygen SpeciesTumor Necrosis Factor-alpha

Identifiers

PMID21153366
PMCPMC3646414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.