ArticleJournal of skin cancer2011
Basal cell carcinomas in gorlin syndrome: a review of 202 patients.
Article in Journal of skin cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 127 citations in OpenAlex.
- Multiple Basal Cell Carcinomas in an Adolescent with an MLPA-DetectedBalkan journal of medical genetics : BJMG · 2026Article
- Challenging interpretation of low-level PTCH1 mosaicism in patients with clinically diagnosed Gorlin syndrome: a case series and review of the literature.Hereditary cancer in clinical practice · 2026Article
- Gorlin-Goltz Syndrome withBalkan medical journal · 2026Article
- Basal Cell Nevus Syndrome and Sporadic Basal Cell Carcinoma: A Comparative Study of Clinicopathological Features.Acta dermato-venereologica · 2025Article
- Further Expanding the Mutational Spectrum of Gorlin Syndrome in Three Unrelated Families.Molecular syndromology · 2024Article
- Hedgehog Inhibitors Beyond Clinical Complete Response in Basal Cell Carcinoma: Should I Stop or Should I Go?The oncologist · 2024Article
- Gorlin Syndrome: A Comprehensive Evaluation of Skin Findings.Turkish archives of pediatrics · 2024Article
- Ultraviolet Radiation Biological and Medical Implications.Current issues in molecular biology · 2024Review
- Pediatric odontogenic keratocyst and early diagnosis of Gorlin syndrome: Clinicopathological aids.The Saudi dental journal · 2024Review
- Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations.International journal of molecular sciences · 2023Review
- Cardiac Fibroma with Asymptomatic Ventricular Arrhythmia in an Adolescent with Gorlin's Syndrome.Journal of pediatric genetics · 2023Article
- An Easily Missed But Life-Threatening Diagnosis: A Case Report of Gorlin Syndrome.The American journal of case reports · 2023Article
- Cardiac Fibroma Presenting With Left Bundle Branch Block in an Adult With Gorlin Syndrome.Texas Heart Institute journal · 2023Article
- Nervous system (NS) Tumors in Cancer Predisposition Syndromes.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Modulation of Hedgehog Signaling for the Treatment of Basal Cell Carcinoma and the Development of Preclinical Models.Biomedicines · 2022Review
- Cancer risk and tumour spectrum in 172 patients with a germlineJournal of medical genetics · 2022Article
- Genodermatoses - Opportunities for Early Detection and Cancer Prevention.Current genetic medicine reports · 2022Review
- Pediatric basal cell carcinoma burden and management preferences in Gorlin syndrome: A survey study.JAAD international · 2021Article
- Current recommendations for cancer surveillance in Gorlin syndrome: a report from the SIOPE host genome working group (SIOPE HGWG).Familial cancer · 2021Article
- Cancer predisposition in pediatric neuro-oncology-practical approaches and ethical considerations.Neuro-oncology practice · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gorlin syndrome (Naevoid Basal Cell Carcinoma Syndrome) is a rare autosomal dominant syndrome caused by mutations in the PTCH gene with a birth incidence of approximately 1 in 19,000. Patients develop multiple basal cell carcinomas of the skin frequently in early life and also have a predisposition to additional malignancies such as medulloblastoma. Gorlin Syndrome patients also have developmental defects such as bifid ribs and other complications such as jaw keratocysts. We studied the incidence and frequency of basal cell carcinomas in 202 Gorlin syndrome patients from 62 families and compared this to their gender and mutation type. Our data suggests that the incidence of basal cell carcinomas is equal between males and females and the mutation type cannot be used to predict disease burden.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.