Evidence map›Paper›PMID 21152105›Full record

ArticlePolymer degradation and stability2010

Storage Stability Study of Salicylate-based Poly(anhydride-esters).

Brittany M Deronde, Ashley L Carbone, Kathryn E Uhrich

Abstract read
In one paragraph

Article in Polymer degradation and stability, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. AnBioinformation · 2024
    Article
  3. Article
  4. Poly(butylene succinate-Royal Society open science · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brittany M DerondeDepartment of Chemistry and Chemical Biology, Rutgers University, 610 Taylor Road, Piscataway, New Jersey, 08854-8087.
Ashley L Carbone
Kathryn E Uhrich

Funding

BIODEGRADABLE POLYMERIC PRODRUGSR01DE013207 · NIDCR · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI UHRICH, KATHRYN ELIZABETH · 2000 to 2009
$2.2M
NIDCR NIH HHS R01 DE013207
6 · The paper itself

Abstract

Storage stability was evaluated on a biodegradable salicylate-based poly(anhydride-ester) to elucidate the effects of storage conditions over time. The hydrolytically labile polymer samples were stored in powdered form at five relevant storage temperatures (-12 °C, 4 °C, 27 °C, 37 °C, 50 °C) and monitored over four weeks for changes in color, glass transition temperature, molecular weight, and extent of hydrolysis. Samples stored at lower temperatures remained relatively constant with respect to bond hydrolysis and molecular weight. Whereas, samples stored at higher temperatures displayed significant hydrolysis. For hydrolytically degradable polymers, such as these poly(anhydride-esters), samples are best stored at low temperatures under an inert atmosphere.

Identifiers

PMID21152105
PMCPMC2997568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.