Evidence map›Paper›PMID 21152075›Full record

ArticleJournal of physics. Condensed matter : an Institute of Physics journal2010

Dehydration and ionic conductance quantization in nanopores.

Michael Zwolak, James Wilson, Massimiliano Di Ventra

Open access · greenAbstract read
In one paragraph

Article in Journal of physics. Condensed matter : an Institute of Physics journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Field-Dependent Dehydration and Optimal Ionic Escape Paths for CThe journal of physical chemistry. B · 2021
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Maxwell-Hall access resistance in graphene nanopores.Physical chemistry chemical physics : PCCP · 2018
    Article
  13. Article
  14. Article
  15. Ionic Coulomb blockade in nanopores.Journal of physics. Condensed matter : an Institute of Physics journal · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael ZwolakTheoretical Division, MS-B213, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
James Wilson
Massimiliano Di Ventra
University of California, San Diego · USLos Alamos National Laboratory · US

Funding

Nanotechnology for the Structural Interrogation of DNAR01HG002647 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RAMSEY, JOHN MICHAEL · 2004 to 2010
$6.3M
NHGRI NIH HHS R01 HG002647
6 · The paper itself

Abstract

There has been tremendous experimental progress in the last decade in identifying the structure and function of biological pores (ion channels) and fabricating synthetic pores. Despite this progress, many questions still remain about the mechanisms and universal features of ionic transport in these systems. In this paper, we examine the use of nanopores to probe ion transport and to construct functional nanoscale devices. Specifically, we focus on the newly predicted phenomenon of quantized ionic conductance in nanopores as a function of the effective pore radius--a prediction that yields a particularly transparent way to probe the contribution of dehydration to ionic transport. We study the role of ionic species in the formation of hydration layers inside and outside of pores. We find that the ion type plays only a minor role in the radial positions of the predicted steps in the ion conductance. However, ions with higher valency form stronger hydration shells, and thus, provide even more pronounced, and therefore, more easily detected, drops in the ionic current. Measuring this phenomenon directly, or from the resulting noise, with synthetic nanopores would provide evidence of the deviation from macroscopic (continuum) dielectric behavior due to microscopic features at the nanoscale and may shed light on the behavior of ions in more complex biological channels.

Indexed as

Models, ChemicalModels, MolecularComputer SimulationIonsNanostructuresParticle SizePorosityWaterIonsWater

Identifiers

PMID21152075
PMCPMC2997750
OpenAlexW2089232284

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.