Evidence map›Paper›PMID 21152043›Full record

ArticlePloS one2010

Accurate determination of phenotypic information from historic thoroughbred horses by single base extension.

Michael G Campana, C Mark Whitten, Ceiridwen J Edwards, Frauke Stock, Angela M Murphy, Matthew M Binns, Graeme W W Barker, Mim A Bower

Abstract read
In one paragraph

Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael G CampanaDepartment of Archaeology, University of Cambridge, Cambridge, United Kingdom. mgc32@cam.ac.uk
C Mark Whitten
Ceiridwen J Edwards
Frauke Stock
Angela M Murphy
Matthew M Binns
Graeme W W Barker
Mim A Bower

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historic DNA data have the potential to identify phenotypic information otherwise invisible in the historical, archaeological and palaeontological record. In order to determine whether a single nucleotide polymorphism typing protocol based on single based extension (SNaPshot™) could produce reliable phenotypic data from historic samples, we genotyped three coat colour markers for a sample of historic Thoroughbred horses for which both phenotypic and correct genotypic information were known from pedigree information in the General Stud Book. Experimental results were consistent with the pedigrees in all cases. Thus we demonstrate that historic DNA techniques can produce reliable phenotypic information from museum specimens.

Indexed as

AllelesAnimalsDNADNA PrimersGenotypeHorsesPaleontologyPedigreePhenotypePolymerase Chain ReactionPolymorphism, Single NucleotideSequence Analysis, DNADNADNA Primers

Identifiers

PMID21152043
PMCPMC2996296

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.