ArticlePloS one2010
Phylogenetic and phyletic studies of informational genes in genomes highlight existence of a 4 domain of life including giant viruses.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 157 citations in OpenAlex.
- The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms.Annual review of biophysics · 2026Review
- Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland.eLife · 2025Article
- Investigations into the Diversity and Distribution of tRNA and Phylogenetics of Translation Factors in Amoebozoa-InfectingViruses · 2025Article
- Host-Calibrated Time Tree Caps the Age of Giant Viruses.Molecular biology and evolution · 2025Article
- Complex Genomes of Early Nucleocytoviruses Revealed by Ancient Origins of Viral Aminoacyl-tRNA Synthetases.Molecular biology and evolution · 2024Article
- Pangenomic Analysis of Nucleo-Cytoplasmic Large DNA Viruses. I: The Phylogenetic Distribution of Conserved Oxygen-Dependent Enzymes Reveals a Capture-Gene Process.Journal of molecular evolution · 2023Article
- Review
- Mimiviruses: Giant viruses with novel and intriguing features (Review).Molecular medicine reports · 2022Review
- Viral histones: pickpocket's prize or primordial progenitor?Epigenetics & chromatin · 2022Review
- The genomes of nucleocytoplasmic large DNA viruses: viral evolution writ large.Microbial genomics · 2021Review
- Rhizomal Reclassification of Living Organisms.International journal of molecular sciences · 2021Review
- Scaling relation between genome length and particle size of viruses provides insights into viral life history.iScience · 2021Article
- Coevolutionary and Phylogenetic Analysis of Mimiviral Replication Machinery Suggest the Cellular Origin of Mimiviruses.Molecular biology and evolution · 2021Article
- Marseilleviruses: An Update in 2021.Frontiers in microbiology · 2021Review
- Eukaryotic and Prokaryotic Microbiota Interactions.Microorganisms · 2020Review
- The origin and evolution of viruses inferred from fold family structure.Archives of virology · 2020Review
- A Place for Viruses on the Tree of Life.Frontiers in microbiology · 2020Review
- Seasonal Dynamics of Algae-Infecting Viruses and Their Inferred Interactions with Protists.Viruses · 2019Article
- Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Two classes of EF1-family translational GTPases encoded by giant viruses.Nucleic acids research · 2019Article
11 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The discovery of Mimivirus, with its very large genome content, made it possible to identify genes common to the three domains of life (Eukarya, Bacteria and Archaea) and to generate controversial phylogenomic trees congruent with that of ribosomal genes, branching Mimivirus at its root. Here we used sequences from metagenomic databases, Marseillevirus and three new viruses extending the Mimiviridae family to generate the phylogenetic trees of eight proteins involved in different steps of DNA processing. Compared to the three ribosomal defined domains, we report a single common origin for Nucleocytoplasmic Large DNA Viruses (NCLDV), DNA processing genes rooted between Archaea and Eukarya, with a topology congruent with that of the ribosomal tree. As for translation, we found in our new viruses, together with Mimivirus, five proteins rooted deeply in the eukaryotic clade. In addition, comparison of informational genes repertoire based on phyletic pattern analysis supports existence of a clade containing NCLDVs clearly distinct from that of Eukarya, Bacteria and Archaea. We hypothesize that the core genome of NCLDV is as ancient as the three currently accepted domains of life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.