ArticleFrontiers in human neuroscience2010
The influence of rest period instructions on the default mode network.
Article in Frontiers in human neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Dwelling in prolonged grief: Resting state functional connectivity during oxytocin and placebo administration.Human brain mapping · 2023Trial
- A systematic review of the impact of stimulus presentation modality on fMRI studies for presurgical mapping.Neuroimage. Reports · 2026Review
- The Scanner as the Stimulus: Deficient Gamma-BOLD Coupling in Schizophrenia at Rest.Schizophrenia bulletin · 2023Article
- Cognition is entangled with metabolism: relevance for resting-state EEG-fMRI.Frontiers in human neuroscience · 2023Article
- Data-Driven EEG Theta and Alpha Components Are Associated with Subjective Experience during Resting State.Journal of personalized medicine · 2022Article
- Aperiodic measures of neural excitability are associated with anticorrelated hemodynamic networks at rest: A combined EEG-fMRI study.NeuroImage · 2021Article
- Patient, interrupted: MEG oscillation dynamics reveal temporal dysconnectivity in schizophrenia.NeuroImage. Clinical · 2020Article
- Quantifying Differences Between Passive and Task-Evoked Intrinsic Functional Connectivity in a Large-Scale Brain Simulation.Brain connectivity · 2018Article
- Increased fMRI activity correlations in autobiographical memory versus resting states.Human brain mapping · 2018Article
- Presurgical language fMRI: Technical practices in epilepsy surgical planning.Human brain mapping · 2018Article
- A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients With Knee Osteoarthritis.The journal of pain · 2018Article
- A Modulatory Effect of Brief Passive Exposure to Non-linguistic Sounds on Intrinsic Functional Connectivity: Relevance to Cognitive Performance.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Cerebral metabolic changes related to clinical parameters in idiopathic anosmic patients during olfactory stimulation: a pilot investigation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Article
- Measuring Pain for Patients Seeking Physical Therapy: Can Functional Magnetic Resonance Imaging (fMRI) Help?Physical therapy · 2017Article
- Auditory Hallucinations and the Brain's Resting-State Networks: Findings and Methodological Observations.Schizophrenia bulletin · 2016Review
- Differential lateralization of hippocampal connectivity reflects features of recent context and ongoing demands: an examination of immediate post-task activity.Human brain mapping · 2015Article
- Cortical metabolic arrangement during olfactory processing: proposal for a 18F FDG PET/CT methodological approach.Medicine · 2014Article
- Default mode network as a potential biomarker of chemotherapy-related brain injury.Neurobiology of aging · 2014Review
- Cortico-subcortical metabolic correlates of olfactory processing in healthy resting subjects.Scientific reports · 2014Article
- Modulation of limbic-cerebellar functional connectivity enables alcoholics to recognize who is who.Brain structure & function · 2013Article
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Authors and funding
7 authors.
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Abstract
The default mode network (DMN) refers to regional brain activity that is greater during rest periods than during attention-demanding tasks; many studies have reported DMN alterations in patient populations. It has also been shown that the DMN is suppressed by scanner background noise (SBN), which is the noise produced by functional magnetic resonance imaging (fMRI). However, it is unclear whether different approaches to "rest" in the noisy MR environment can alter the DMN and constitute a confound in studies investigating the DMN in particular patient populations (e.g., individuals with schizophrenia, Alzheimer's disease). We examined 27 healthy adult volunteers who completed an fMRI experiment with three different instructions for rest: (1) relax and be still, (2) attend to SBN, or (3) ignore SBN. Region of interest analyses were performed to determine the influence of rest period instructions on core regions of the DMN and DMN regions previously reported to be altered in patients with or at risk for Alzheimer's disease or schizophrenia. The dorsal medial prefrontal cortex (dmPFC) exhibited greater activity when specific resting instructions were given (i.e., attend to or ignore SBN) compared to when non-specific resting instructions were given. Condition-related differences in connectivity were also observed between regions of the dmPFC and inferior parietal/posterior superior temporal cortex. We conclude that rest period instructions and SBN levels should be carefully considered for fMRI studies on the DMN, especially studies on clinical populations and groups that may have different approaches to rest, such as first-time research participants and children.
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