Evidence map›Paper›PMID 21151647›Full record

ReviewJournal of biomedicine & biotechnology2011

Surgical approaches to create murine models of human wound healing.

Victor W Wong, Michael Sorkin, Jason P Glotzbach, Michael T Longaker, Geoffrey C Gurtner

Abstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 198 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Life (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice.Experimental biology and medicine (Maywood, N.J.) · 2026
    Article
  16. Article
  17. Relaxin-2 drives regenerative healing and suppresses scar formation.bioRxiv : the preprint server for biology · 2025
    Article
  18. Review
  19. Article
  20. Article

138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victor W WongDepartment of Surgery, Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University, 257 Campus Drive, GK210, Stanford, CA 94305, USA.
Michael Sorkin
Jason P Glotzbach
Michael T Longaker
Geoffrey C Gurtner

Funding

Reversal of Progenitor Cell Deficits in DiabetesR01DK074095 · NIDDK · UNIVERSITY OF ARIZONA · PI GURTNER, GEOFFREY C · 2005 to 2025
$6.4M
Inside-Out Tissue Engineering for Organ FabricationR01EB005718 · NIBIB · STANFORD UNIVERSITY · PI GURTNER, GEOFFREY C, LONGAKER, MICHAEL T · 2010 to 2013
$1.4M
Progenitor Cell Dysfunction and Impaired Neovascularization in DiabetesR56DK074095 · NIDDK · STANFORD UNIVERSITY · PI BROWNLEE, MICHAEL A, GURTNER, GEOFFREY C · 2009 to 2009
$500k
NIBIB NIH HHS R01 EB005718NIBIB NIH HHS R01EB-005718NIDDK NIH HHS R01/R56DK-074095NIDDK NIH HHS R56 DK074095
6 · The paper itself

Abstract

Wound repair is a complex biologic process which becomes abnormal in numerous disease states. Although in vitro models have been important in identifying critical repair pathways in specific cell populations, in vivo models are necessary to obtain a more comprehensive and pertinent understanding of human wound healing. The laboratory mouse has long been the most common animal research tool and numerous transgenic strains and models have been developed to help researchers study the molecular pathways involved in wound repair and regeneration. This paper aims to highlight common surgical mouse models of cutaneous disease and to provide investigators with a better understanding of the benefits and limitations of these models for translational applications.

Indexed as

Disease Models, AnimalSkin TransplantationWound HealingAnimalsHumansMice

Identifiers

PMID21151647
PMCPMC2995912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.