ArticleInternational journal of molecular sciences2010
Involvement of Glutamate transporter-1 in neuroprotection against global brain ischemia-reperfusion injury induced by postconditioning in rats.
Article in International journal of molecular sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Cerebroprotective Potential of Androgen Receptors in Ischemic Postconditioning against Cerebral Ischemia/Reperfusion-induced Neurodegenerative Changes.Central nervous system agents in medicinal chemistry · 2026Article
- Remote Ischaemic Preconditioning Accelerates Brain to Blood Glutamate Efflux via EAATs-mediated Transport.Neurochemical research · 2023Article
- Neuroprotective Mechanism of Hypoxic Post-conditioning Involves HIF1-Associated Regulation of the Pentose Phosphate Pathway in Rat Brain.Neurochemical research · 2019Article
- Spreading depolarization and neuronal damage or survival in mouse neocortical brain slices immediately and 12 hours following middle cerebral artery occlusion.Journal of neurophysiology · 2019Article
- Article
- Cerebral Ischemic Postconditioning Plays a Neuroprotective Role through Regulation of Central and Peripheral Glutamate.BioMed research international · 2018Review
- MODULATION OF KEY BIOCHEMICAL MARKERS RELEVANT TO STROKE BYAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017Article
- Buyang Huanwu decoction increases the expression of glutamate transporter-1 and glutamate synthetase in association with PACAP-38 following focal ischemia.Biomedical reports · 2015Article
- The Role of NMDA Receptors in the Development of Brain Resistance through Pre- and Postconditioning.Aging and disease · 2014Review
- Biological networks in ischemic tolerance - rethinking the approach to clinical conditioning.Translational stroke research · 2013Review
- Article
- From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia.Current drug targets · 2012Review
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Authors and funding
6 authors.
Funding
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Abstract
Ischemic postconditioning refers to several transient reperfusion and ischemia cycles after an ischemic event and before a long duration of reperfusion. The procedure produces neuroprotective effects. The mechanisms underlying these neuroprotective effects are poorly understood. In this study, we found that most neurons in the CA1 region died after 10 minutes of ischemia and is followed by 72 hours of reperfusion. However, brain ischemic postconditioning (six cycles of 10 s/10 s reperfusion/re-occlusion) significantly reduced neuronal death. Significant up-regulation of Glutamate transporter-1 was found after 3, 6, 24, 72 hours of reperfusion. The present study showed that ischemic postconditioning decreases cell death and that upregulation of GLT-1 expression may play an important role on this effect.
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