ReviewPediatric endocrinology reviews : PER2010
Genetic and epigenetic influences associated with intrauterine growth restriction due to in utero tobacco exposure.
Review in Pediatric endocrinology reviews : PER, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Screening, investigation and follow-up of neonates with small for gestational age in a metropolitan hospital in Australia-observational retrospective study.Translational pediatrics · 2024Article
- Maternal and early life exposures and their potential to influence development of the microbiome.Genome medicine · 2022Review
- Effect of E-cigarettes aerosol exposure during lactation in rats: Hormonal and biochemical aspects.Environmental toxicology and pharmacology · 2021Article
- Epigenetic Alterations of Maternal Tobacco Smoking during Pregnancy: A Narrative Review.International journal of environmental research and public health · 2021Review
- The impact of tobacco chemicals and nicotine on placental development.Prenatal diagnosis · 2020Review
- The Development of the Human Microbiome: Why Moms Matter.Gastroenterology clinics of North America · 2019Review
- Epigenetic signature of preterm birth in adult twins.Clinical epigenetics · 2018Article
- DNA Methylation Profiling at Single-Base Resolution Reveals Gestational Folic Acid Supplementation Influences the Epigenome of Mouse Offspring Cerebellum.Frontiers in neuroscience · 2016Article
- DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring.International journal of epidemiology · 2015Article
- Is there evidence for potential harm of electronic cigarette use in pregnancy?Birth defects research. Part A, Clinical and molecular teratology · 2015Review
- Physical, behavioral, and cognitive effects of prenatal tobacco and postnatal secondhand smoke exposure.Current problems in pediatric and adolescent health care · 2014Review
- Does low birth weight share common genetic or environmental risk with childhood disruptive disorders?Journal of abnormal psychology · 2013Article
- Maternal smoking as a model for environmental epigenetic changes affecting birthweight and fetal programming.Molecular human reproduction · 2013Review
- What changes in DNA methylation take place in individuals exposed to maternal smoking in utero?Epigenomics · 2012Article
- Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression.Epigenetics · 2011Article
- Maternal tobacco use is associated with increased markers of oxidative stress in the placenta.American journal of obstetrics and gynecology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
While many fetuses are exposed to tobacco in utero, not all experience adverse outcomes as a result of this exposure. Mechanisms leading to the attenuation of fetal birth weight and adverse pregnancy outcomes are complex. Therefore many studies have begun to focus, not only on the contribution of maternal and fetal genes to phenotypic outcome, but also on epigenetic changes associated with exposure to maternal tobacco smoke. In this review, we detail the epidemiologic evidence associating an adverse pregnancy outcome to maternal tobacco use. We provide a brief summary of studies demonstrating an association between maternal and fetal gene polymorphisms with low birth weight in response to maternal tobacco exposure. We also review the literature showing epigenetic changes in the offspring associated with in utero tobacco exposure. The complex interplay of genomic and epigenomic factors may contribute to specific phenotypic outcomes and can help begin to elucidate the differential susceptibilities to tobacco smoke in utero.
Indexed as
Identifiers
21150839PMC5084836W2415900780What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.