Evidence map›Paper›PMID 21149826›Full record

ReviewHypertension (Dallas, Tex. : 1979)2011

Inflammation, immunity, and hypertension.

David G Harrison, Tomasz J Guzik, Heinrich E Lob, Meena S Madhur, Paul J Marvar, Salim R Thabet, Antony Vinh, Cornelia M Weyand

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 438 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
438citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

438 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Beyond the guidelines: Vascular function as the central determinant and therapeutic target in hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  4. Article
  5. HMGB1 as a danger signal in vascular remodeling.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Special Issue: Recent Research on Hypertension and Related Complications.International journal of molecular sciences · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Maresin 1 modulates renal and cardiac lipid profiles in hypertensive rats.American journal of physiology. Renal physiology · 2025
    Article
  20. Article

378 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David G HarrisonDivision of Clinical Pharmacology, Vanderbilt University, Nashville, TN 37232-6602, USA. endocelldoc@mac.com
Tomasz J Guzik
Heinrich E Lob
Meena S Madhur
Paul J Marvar
Salim R Thabet
Antony Vinh
Cornelia M Weyand

Funding

Vascular specific ACE expression and atherosclerosisP01HL058000 · NHLBI · VANDERBILT UNIVERSITY · PI HARRISON, DAVID G · 1998 to 2013
$20.7M
T cell triggering events and hypertensionP01HL095070 · NHLBI · EMORY UNIVERSITY · PI GRIENDLING, KATHY K · 2009 to 2019
$20.5M
REGULATION OF VASCULAR FUNCTION BY THE ENDOTHELIUMR01HL039006 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRISON, DAVID G · 1987 to 2017
$5.5M
Roles of oxidation and inflammation in aortic stiffeningR01HL105294 · NHLBI · VANDERBILT UNIVERSITY · PI HARRISON, DAVID G · 2010 to 2013
$1.5M
NHLBI NIH HHS P01 HL058000NHLBI NIH HHS P01HL058000NHLBI NIH HHS P01 HL095070NHLBI NIH HHS P01HL095070NHLBI NIH HHS R01 HL039006NHLBI NIH HHS R01HL039006NHLBI NIH HHS R01 HL105294
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptive ImmunityAnimalsCytokinesHumansHypertensionImmunityImmunity, InnateInflammationModels, ImmunologicalT-LymphocytesCytokines

Identifiers

PMID21149826
PMCPMC3028593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.