Evidence map›Paper›PMID 21149356›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2011

Infection in conflict wounded.

W G P Eardley, K V Brown, T J Bonner, A D Green, J C Clasper

Registry-linked trialOpen access · bronzeAbstract readHistorical ArticleReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02744144 (Wound Bacterial Microbiota and Their Antibiotic Resistance), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02744144 completednot on this mapstarted 2014, after this paper: background citation

Wound Bacterial Microbiota and Their Antibiotic Resistance: a Prospective Cohort Study of Hospitalized Patients Originating From the Syrian Armed Conflict

TypeobservationalSponsorKarolinska InstitutetRan2014 to 2016Enrolled457ConditionsWounds and Injuries, War-Related Injuries, Wound Infection, Wounds, Penetrating
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. The intersection of fracture healing and infection: Orthopaedics research society workshop 2021.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

W G P EardleyAcademic Department of Military Trauma and Surgery, Royal Centre for Defence Medicine, Academic and Research Directorate, West Wing, Institute of Research and Development, Vincent Drive, Birmingham B15 2SQ, UK.
K V Brown
T J Bonner
A D Green
J C Clasper
Birmingham Research Park · GBGoogle (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mechanisms of modern military wounding may be distinct from those of ancient conflicts, the infectious sequelae of ballistic trauma and the evolving microbial flora of war wounds remain a considerable burden on both the injured combatant and their deployed medical systems. Battlefield surgeons of ancient times favoured suppuration in war wounding and as such Galenic encouragement of pus formation would hinder progress in wound care for centuries. Napoleonic surgeons eventually abandoned this mantra, embracing radical surgical intervention, primarily by amputation, to prevent infection. Later, microscopy enabled identification of microorganisms and characterization of wound flora. Concurrent advances in sanitation and evacuation enabled improved outcomes and establishment of modern military medical systems. Advances in medical doctrine and technology afford those injured in current conflicts with increasing survivability through rapid evacuation, sophisticated resuscitation and timely surgical intervention. Infectious complications in those that do survive, however, are a major concern. Addressing antibiotic use, nosocomial transmission and infectious sequelae are a current clinical management and research priority and will remain so in an era characterized by a massive burden of combat extremity injury. This paper provides a review of infection in combat wounding from a historical setting through to the modern evidence base.

Indexed as

Military PersonnelWarfareAcinetobacterAnti-Infective AgentsBandagesCross InfectionHistory, 19th CenturyHistory, 20th CenturyHistory, 21st CenturyHistory, AncientHistory, MedievalHumansMilitary MedicineWound InfectionAnti-Infective Agents

Identifiers

PMID21149356
PMCPMC3013428
OpenAlexW2163697617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.