Evidence map›Paper›PMID 21148754›Full record

ReviewEukaryotic cell2011

Initial cell type choice in Dictyostelium.

Wonhee Jang, Richard H Gomer

Abstract readReview
In one paragraph

Review in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Precarious development: the uncertain social life of cellular slime molds.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  9. Article
  10. Review
  11. Article
  12. Evolution of cooperation and control of cheating in a social microbe.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wonhee JangDepartment of Life Science, Dongguk University, 3-26 Pil-dong, Jung-gu, Seoul 100-715, South Korea. wany@dongguk.edu
Richard H Gomer

Funding

An autocrine repressor of cell proliferationR01GM074990 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI GOMER, RICHARD H · 2006 to 2009
$1.1M
NIGMS NIH HHS R01 GM074990
6 · The paper itself

Abstract

Much remains to be understood about how a group of cells break symmetry and differentiate into distinct cell types. The simple eukaryote Dictyostelium discoideum is an excellent model system for studying questions such as cell type differentiation. Dictyostelium cells grow as single cells. When the cells starve, they aggregate to develop into a multicellular structure with only two main cell types: spore and stalk. There has been a longstanding controversy as to how a cell makes the initial choice of becoming a spore or stalk cell. In this review, we describe how the controversy arose and how a consensus developed around a model in which initial cell type choice in Dictyostelium is dependent on the cell cycle phase that a cell happens to be in at the time that it starves.

Indexed as

Cell DifferentiationAnimalsCell CycleDictyosteliumGene Expression ProfilingNeutral RedSpores, ProtozoanStaining and LabelingStarvationNeutral Red

Identifiers

PMID21148754
PMCPMC3067408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.