ArticleApplied and environmental microbiology2011
Integrity of proteins in human saliva after sterilization by gamma irradiation.
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Limosilactobacillus reuteri DSM 17938 Inhibition of Biofilm Formation by Prevotella intermedia and Fusobacterium nucleatum Across Salivary pH: An In Vitro Study.European journal of dentistry · 2025Article
- Nitrates of cerium and samarium deposit on human enamel independently of a salivary pellicle.Frontiers in oral health · 2024Article
- Effect of Surface Tooling Techniques of Medical Titanium Implants on Bacterial Biofilm Formation In Vitro.Materials (Basel, Switzerland) · 2022Article
- CPC-containing oral rinses inactivate SARS-CoV-2 variants and are active in the presence of human saliva.Journal of medical microbiology · 2022Article
- EDX-analysis of fluoride precipitation on human enamel.Scientific reports · 2019Article
- "The Smartphone's Guide to the Galaxy": In Situ Analysis in Space.Biosensors · 2018Review
- Activity of taurolidine gels on ex vivo periodontal biofilm.Clinical oral investigations · 2018Article
- In vitro effects of hydroxyapatite containing toothpastes on dentin permeability after multiple applications and ageing.Scientific reports · 2018Article
- Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage.Frontiers in microbiology · 2018Article
- Nanopore DNA Sequencing and Genome Assembly on the International Space Station.Scientific reports · 2017Article
- Identification of Factors Associated with Biofilm Formation Ability in the Clinical Isolates ofIranian journal of biotechnology · 2017Article
- Effect of Different Obturation Materials on Residual Antimicrobial Activity of 2% Chlorhexidine in Dentin at Different Time Intervals: An Ex Vivo Study.Journal of dentistry (Tehran, Iran) · 2015Article
- The scientific exploration of saliva in the post-proteomic era: from database back to basic function.Expert review of proteomics · 2012Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Microbial contamination of whole human saliva is unwanted for certain in vitro applications, e.g., when utilizing it as a growth substratum for biofilm experiments. The aim of this investigation was to test gamma irradiation for its suitability to sterilize saliva and to investigate the treatment's influence on the composition and integrity of salivary proteins in comparison to filter sterilization. For inhibition of bacterial growth by gamma irradiation, a sterility assurance level of 10(-6) was determined to be reached at a dose of 3.5 kGy. At this dose, the integrity of proteins, as measured by fluorescence, circular dichroism, and gel electrophoretic banding pattern, and the enzymatic activities of salivary amylase and lysozyme were virtually unchanged. Filtration reduced the total protein concentration to about half of its original value and decreased lysozyme activity to about 10%. It can be concluded that irradiation is suitable for sterilizing whole saliva in its native form.
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