ArticleAmerican journal of epidemiology2011
Effect of dietary fiber intake on lipoprotein cholesterol levels independent of estradiol in healthy premenopausal women.
Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Implementation and reporting of causal mediation analysis in 2015: a systematic review in epidemiological studies.BMC research notes · 2016Pooled it
- Recent Progress in Exploring Dietary Nutrition and Dietary Patterns in Periodontitis with a Focus on SCFAs.Nutrients · 2025Review
- Exploring the cholesterol-lowering effects of cereal bran cell wall-enriched diets.Food science & nutrition · 2024Article
- Nutrient scoring for the DEGS1-FFQ - from food intake to nutrient intake.BMC nutrition · 2023Article
- Performance of the Global Diet Quality Score with Nutrition and Health Outcomes in Mexico with 24-h Recall and FFQ Data.The Journal of nutrition · 2021Article
- The role of ideation on the effect of an SBC intervention on consistent bed net use among caregivers of children under 5 years in Nigeria: a multilevel mediation analysis.BMC public health · 2021Article
- Effect of thermally treated barley dietary fiber against hypercholesterolemia.Food science & nutrition · 2020Article
- Health Benefits of Lactic Acid Bacteria (LAB) Fermentates.Nutrients · 2020Review
- Article
- Does Partner Selection Mediate the Relationship Between School Attendance and HIV/Herpes Simplex Virus-2 Among Adolescent Girls and Young Women in South Africa: An Analysis of HIV Prevention Trials Network 068 Data.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Dietary fiber intake and its association with indicators of adiposity and serum biomarkers in European adolescents: the HELENA study.European journal of nutrition · 2015Article
- The effects of the DASH diet education program with omega-3 fatty acid supplementation on metabolic syndrome parameters in elderly women with abdominal obesity.Nutrition research and practice · 2015Article
- Lipid concentrations and couple fecundity: the LIFE study.The Journal of clinical endocrinology and metabolism · 2014Article
- Undaria pinnatifida soluble fiber regulates Angptl3-LPL pathway to lessen hyperlipidemia in mice.Journal of physiology and biochemistry · 2013Article
- Changes in weight loss and lipid profiles after a dietary purification program: a prospective case series.Journal of chiropractic medicine · 2013Article
- Phytoestrogen and fiber intakes in relation to incident vasomotor symptoms: results from the Study of Women's Health Across the Nation.Menopause (New York, N.Y.) · 2013Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
High-fiber diets are associated with improved lipid profiles. However, pre- and postmenopausal women respond differently to fiber intake, suggesting that endogenous estradiol mediates the effect. The authors' objective was to determine the direct effect of fiber intake on lipoprotein cholesterol levels independent of estradiol among premenopausal women. The BioCycle Study, a prospective cohort study conducted at the State University of New York at Buffalo from 2005 to 2007, followed 259 healthy women for up to 2 complete menstrual cycles. Serum lipoprotein and hormone levels were measured at 16 visits timed using fertility monitors. Fiber intake was assessed by 8 24-hour recalls. Marginal structural models with inverse probability weights for both lipoprotein and estradiol levels were used to estimate controlled direct effects of the highest category of fiber intake (≥22 g/day vs. <22 g/day) while accounting for age, body mass index, total energy, vitamin E intake, physical activity, luteinizing hormone, follicle-stimulating hormone, and progesterone. Reductions were observed in total and low density lipoprotein cholesterol in women with higher fiber intakes. Direct effects were greater than total effects. These analyses suggested that estradiol mediates at least part of the association between fiber and cholesterol among premenopausal women. More research is needed to elucidate the biologic mechanisms driving these associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.