Evidence map›Paper›PMID 21147729›Full record

ReviewCirculation2010

Genetic cardiovascular risk prediction: will we get there?

George Thanassoulis, Ramachandran S Vasan

Abstract readReview
In one paragraph

Review in Circulation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Association between the ESR1 -351A>G single nucleotide polymorphism (rs9340799) and adolescent idiopathic scoliosis: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. The Use of AI for Phenotype-Genotype Mapping.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  8. Article
  9. Article
  10. Hypertension is associated with a variant in theInternational journal of molecular epidemiology and genetics · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genetic Markers for Coronary Artery Disease.Medicina (Kaunas, Lithuania) · 2018
    Review
  16. Genetics of Cardiovascular Disease: Fishing for Causality.Frontiers in cardiovascular medicine · 2018
    Review
  17. Article
  18. Association between theOncotarget · 2017
    Article
  19. Article
  20. Mitochondrial DNA mutations and cardiovascular disease.Current opinion in cardiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

George ThanassoulisFramingham Heart Study, 73 Mt Wayte, #2, Framingham, MA 01702-5803, USA. vasan@bu.edu
Ramachandran S Vasan

Funding

Genome-wide Association Study of Cardiac Structure and FunctionR01HL093328 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2008 to 2011
$2.4M
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
CIHRNHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NHLBI NIH HHS R01 HL093328NHLBI NIH HHS R01-HL93328
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlgorithmsCardiovascular DiseasesGenetic Predisposition to DiseaseGenetic TestingHumansPolymorphism, Single NucleotidePredictive Value of TestsRisk Factors

Identifiers

PMID21147729
PMCPMC3075800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.