ArticleEuropean journal of medical research2010
Interaction of arachidonic acid with electrogenic properties of mouse chemosensory neurons.
Article in European journal of medical research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 5 citations in OpenAlex.
- Absence of bioactivity of lipid derivatives of serotonin.European journal of medical research · 2010Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemosensory neurons respond to stimulation induced by gasses, volatile and non-volatile compounds. Neuronal excitation mediated via second messengers involves typically: cGMP, cAMP, or IP⊂3. Transduction pathways based on cyclic nucleotide have three-phosphate nucleotide as substrate, while IP⊂3 has a membrane lipid substrate. These derivatives of cholesterol are signaling molecules with modulator-like effects on many proteins, including membrane ion channels. In the present study, spontaneous and induced activities were recorded in a whole-cell configuration, in current and voltage clamp modes, in isolated chemosensory neurons obtained from the mouse. Chemosensory neurons responded with an inward depolarizing current to application of arachidonic acid, which suggests a role for it in putative mechanisms of signal transduction.
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Registered trials
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