ArticleEnvironmental health perspectives2011
Cancer risks near nuclear facilities: the importance of research design and explicit study hypotheses.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Incidence of solid cancers among residents near nuclear facilities: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Health Effects of Occupational and Environmental Exposures to Nuclear Power Plants: A Meta-Analysis and Meta-Regression.Current environmental health reports · 2024Pooled it
- Cancer incidence near nuclear facilities in Korea (2005-2022): implications of regional socioeconomic status and industrial context.BMC public health · 2026Article
- Radioactive releases from the nuclear power sector and implications for child health.BMJ paediatrics open · 2022Review
- Brain cancer incidence rates and the presence of nuclear reactors in US states: a hypothesis-generating study.Environmental geochemistry and health · 2021Article
- Disproportionate Impacts of Radiation Exposure on Women, Children, and Pregnancy: Taking Back our Narrative.Journal of the history of biology · 2021Article
- Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level.International journal of cancer · 2020Article
- Cancer incidence surrounding the former Apollo nuclear facility 1990-2010.Journal of exposure science & environmental epidemiology · 2019Article
- Reanalysis of Epidemiological Investigation of Cancer Risk among People Residing near Nuclear Power Plants in South Korea.International journal of environmental research and public health · 2018Article
- Thyroid Cancer Incidence around the Belgian Nuclear Sites, 2000-2014.International journal of environmental research and public health · 2017Article
- Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay.British journal of cancer · 2014Article
- Re: cancer risk in adult residents near nuclear power plants in Korea: a cohort study of 1992-2010.Journal of Korean medical science · 2014Article
- Epidemiological evidence of childhood leukaemia around nuclear power plants.Dose-response : a publication of International Hormesis Society · 2014Article
- The risk of leukaemia in young children from exposure to tritium and carbon-14 in the discharges of German nuclear power stations and in the fallout from atmospheric nuclear weapons testing.Radiation and environmental biophysics · 2014Article
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Authors and funding
3 authors.
Funding
Abstract
backgroundIn April 2010, the U.S. Nuclear Regulatory Commission asked the National Academy of Sciences to update a 1990 study of cancer risks near nuclear facilities. Prior research on this topic has suffered from problems in hypothesis formulation and research design.
objectivesWe review epidemiologic principles used in studies of generic exposure-response associations and in studies of specific sources of exposure. We then describe logical problems with assumptions, formation of testable hypotheses, and interpretation of evidence in previous research on cancer risks near nuclear facilities. DISCUSSION: Advancement of knowledge about cancer risks near nuclear facilities depends on testing specific hypotheses grounded in physical and biological mechanisms of exposure and susceptibility while considering sample size and ability to adequately quantify exposure, ascertain cancer cases, and evaluate plausible confounders.
conclusionsNext steps in advancing knowledge about cancer risks near nuclear facilities require studies of childhood cancer incidence, focus on in utero and early childhood exposures, use of specific geographic information, and consideration of pathways for transport and uptake of radionuclides. Studies of cancer mortality among adults, cancers with long latencies, large geographic zones, and populations that reside at large distances from nuclear facilities are better suited for public relations than for scientific purposes.
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