Evidence map›Paper›PMID 21147473›Full record

ReviewTopics in companion animal medicine2010

Feline genetics: clinical applications and genetic testing.

Leslie A Lyons

Open access · greenAbstract readReview
In one paragraph

Review in Topics in companion animal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. DNA mutations of the cat: the good, the bad and the ugly.Journal of feline medicine and surgery · 2015
    Review
  10. Article
  11. Article
  12. A web resource on DNA tests for canine and feline hereditary diseases.Veterinary journal (London, England : 1997) · 2013
    Article
  13. Article
  14. Feline deafness.The Veterinary clinics of North America. Small animal practice · 2012
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Leslie A LyonsDepartment of Population Health & Reproduction, University of California, Davis, CA, USA. lalyons@ucdavis.edu
University of California, Davis · US

Funding

Genetic Mapping Resources for Common Mammalian DiseasesR24RR016094 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI LYONS, LESLIE A · 2002 to 2011
$3.0M
NCRR NIH HHS R24 RR016094
6 · The paper itself

Abstract

DNA testing for domestic cat diseases and appearance traits is a rapidly growing asset for veterinary medicine. Approximately 33 genes contain 50 mutations that cause feline health problems or alterations in the cat's appearance. A variety of commercial laboratories can now perform cat genetic diagnostics, allowing both the veterinary clinician and the private owner to obtain DNA test results. DNA is easily obtained from a cat via a buccal swab with a standard cotton bud or cytological brush, allowing DNA samples to be easily sent to any laboratory in the world. The DNA test results identify carriers of the traits, predict the incidence of traits from breeding programs, and influence medical prognoses and treatments. An overall goal of identifying these genetic mutations is the correction of the defect via gene therapies and designer drug therapies. Thus, genetic testing is an effective preventative medicine and a potential ultimate cure. However, genetic diagnostic tests may still be novel for many veterinary practitioners and their application in the clinical setting needs to have the same scrutiny as any other diagnostic procedure. This article will review the genetic tests for the domestic cat, potential sources of error for genetic testing, and the pros and cons of DNA results in veterinary medicine. Highlighted are genetic tests specific to the individual cat, which are a part of the cat's internal genome.

Indexed as

BreedingAnimalsCat DiseasesCatsDNAFemaleGenetic Diseases, InbornGenetic MarkersGenetic TestingGenetic TherapyMaleMutationSelection, GeneticDNAGenetic Markers

Identifiers

PMID21147473
PMCPMC3073564
OpenAlexW2036149306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.