ReviewHearing research2011
Tinnitus: Models and mechanisms.
Review in Hearing research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Audiovestibular Dysfunction Related to Long COVID-19 Syndrome: A Systematic Review of Characteristics, Pathophysiology, Diagnosis, and Management.International journal of molecular sciences · 2026Pooled it
- The efficacy of transcranial random noise stimulation in treating tinnitus: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Pooled it
- Tinnitus and event related potentials: a systematic review.Brazilian journal of otorhinolaryngologyPooled it
- Association Between Subjective Tinnitus and Cervical Spine or Temporomandibular Disorders: A Systematic Review.Trends in hearingPooled it
- Photobiomodulation with near-infrared laser for tinnitus management: preliminary animal experiments and randomized clinical trials.Lasers in medical science · 2024Trial
- Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans.Science translational medicine · 2018Trial
- BOLD fMRI effects of transcutaneous vagus nerve stimulation in patients with chronic tinnitus.PloS one · 2018Trial
- Trial
- L-type calcium channel modulation reveals the relationship between neuronal synchrony and hyperactivity in the inferior colliculus following noise-induced hearing loss.Scientific reports · 2025Article
- Modulation of Auditory Cortex Activity in Salicylate-Induced Tinnitus Rats via Deep Brain Stimulation of the Inferior Colliculus.Brain and behavior · 2025Article
- NMDA Receptors: Next therapeutic targets for Tinnitus?Biochemistry and biophysics reports · 2025Review
- Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC).Scientific reports · 2025Article
- Distinctive clinical features of early and late-onset Ménière's disease.Frontiers in neurology · 2025Article
- Effects of Personality Traits on the Severity of Chronic Subjective Tinnitus: A Cross-Sectional Analysis.Medicina (Kaunas, Lithuania) · 2024Article
- Sensory Inhibition and Tinnitus: Measurement of Auditory Gating.Seminars in hearing · 2024Review
- Exploring the interplay of depression, sleep quality, and hearing in tinnitus-related handicap: insights from polysomnography and pure-tone audiometry.BMC psychiatry · 2024Article
- Glycine is a transmitter in the human and chimpanzee cochlear nuclei.Frontiers in neuroanatomy · 2024Article
- Eavesdropping on Tinnitus Using MEG: Lessons Learned and Future Perspectives.Journal of the Association for Research in Otolaryngology : JARO · 2023Review
- Evidence of cochlear neural degeneration in normal-hearing subjects with tinnitus.Scientific reports · 2023Article
- An MR spectroscopy study of temporal areas excluding primary auditory cortex and frontal regions in subjective bilateral and unilateral tinnitus.Scientific reports · 2023Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Over the past decade, there has been a burgeoning of scientific interest in the neurobiological origins of tinnitus. During this period, numerous behavioral and physiological animal models have been developed which have yielded major clues concerning the likely neural correlates of acute and chronic forms of tinnitus and the processes leading to their induction. The data increasingly converge on the view that tinnitus is a systemic problem stemming from imbalances in the excitatory and inhibitory inputs to auditory neurons. Such changes occur at multiple levels of the auditory system and involve a combination of interacting phenomena that are triggered by loss of normal input from the inner ear. This loss sets in motion a number of plastic readjustments in the central auditory system and sometimes beyond the auditory system that culminate in the induction of aberrant states of activation that include hyperactivity, bursting discharges and increases in neural synchrony. This article will review was has been learned about the biological origins of these alterations, summarize where they occur and examine the cellular and molecular mechanisms that are most likely to underlie them.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.