Evidence map›Paper›PMID 21146126›Full record

ReviewSeminars in nephrology2010

Acute kidney injury in hematopoietic cell transplantation.

Amy Kogon, Sangeeta Hingorani

Abstract readReview
In one paragraph

Review in Seminars in nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  7. Review
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  17. Acute kidney injury in the patient with cancer.Kidney research and clinical practice · 2019
    Review
  18. Article
  19. Article
  20. The Impact of Toxicities on First-Year Outcomes after Ex Vivo CD34Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amy KogonDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
Sangeeta Hingorani

Funding

Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
Chronic kidney disease in survivors of hematopoietic cell transplantR01DK080860 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI HINGORANI, SANGEETA · 2008 to 2012
$1.6M
NIDDK NIH HHS R01 DK080860NIDDK NIH HHS T32 DK007662
6 · The paper itself

Abstract

Hematopoietic cell transplantation is becoming an increasingly common treatment modality for a variety of diseases. However, patient survival may be limited by substantial treatment-related toxicities, including acute kidney injury (AKI). AKI can develop in approximately 70% of patients posttransplant and is associated with an increased risk of morbidity and mortality. The development of AKI varies depending on the type of conditioning regimen used and the donor cells infused at the time of transplant, and the etiology often is multifactorial. Epidemiology, risk factors for development, pathogenesis, and potential treatment options for AKI in the hematopoietic cell transplantation population are reviewed as well as newer data on early markers of renal injury. As the indications for and number of transplants performed each year increases, nephrologists and oncologists will have to work together to identify patients who are at risk for AKI to both prevent its development and initiate therapy early to improve outcomes.

Indexed as

Acute Kidney InjuryGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunosuppressive AgentsIncidenceMyeloablative AgonistsTransplantation, AutologousTransplantation, HomologousImmunosuppressive AgentsMyeloablative Agonists

Identifiers

PMID21146126
PMCPMC3432413

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.