Evidence map›Paper›PMID 21145496›Full record

ArticleDevelopmental cell2010

"TORCing" neutrophil chemotaxis.

Pascale G Charest, Richard A Firtel

Open access · bronzeAbstract readComment
In one paragraph

Article in Developmental cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Signaling mechanisms for chemotaxis.Development, growth & differentiation · 2011
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pascale G CharestUniversity of California, San Diego, La Jolla, 92093-0380, USA.
Richard A Firtel
University of California San Diego · US

Funding

SIGNALLING PROCESSES IN DICTYOSTELIUMR01GM037830 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRTEL, RICHARD A · 1986 to 2015
$8.5M
Quantitative Analysis of Chemotactic Motility Cycle of Ameboid CellsR01GM084227 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEL ALAMO, JUAN CARLOS, FIRTEL, RICHARD A · 2010 to 2018
$2.7M
NIGMS NIH HHS R01 GM037830NIGMS NIH HHS R01 GM084227
6 · The paper itself

Abstract

During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils.

Identifiers

PMID21145496
PMCPMC3033560
OpenAlexW2090916534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.