Evidence map›Paper›PMID 21145454›Full record

ArticleCell2010

Lipid trafficking sans vesicles: where, why, how?

William A Prinz

Abstract read
In one paragraph

Article in Cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
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  3. Article
  4. Article
  5. Review
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  9. Article
  10. Article
  11. NPC1-dependent alterations in KNature communications · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Phosphoinositide transport and metabolism at membrane contact sites.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Review
  17. Intracellular Cholesterol Synthesis and Transport.Frontiers in cell and developmental biology · 2022
    Review
  18. Review
  19. Review
  20. Vps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

William A PrinzLaboratory of Cell Biochemistry and Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. williamp@intra.niddk.nih.gov

Funding

Intracellular Lipid Trafficking and Organelle BiogenesisZIADK060004 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI PRINZ, WILLIAM · 2009 to 2022
$8.5M
Intracellular Lipid Trafficking and Organelle BiogenesisZ01DK060004 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI PRINZ, WILLIAM · 2002 to 2008
$532k
Intramural NIH HHS Z01 DK060004
6 · The paper itself

Abstract

Eukaryotic cells possess a remarkable diversity of lipids, which distribute among cellular membranes by well-characterized vesicle trafficking pathways. However, transport of lipids by alternate, or "nonvesicular," routes is also critical for lipid synthesis, metabolism, and proper membrane partitioning. In the past few years, considerable progress has been made in characterizing the mechanisms of nonvesicular lipid transport and how it may go awry in particular diseases, but many fundamental questions remain for this rising field.

Indexed as

Lipid MetabolismAnimalsBiological TransportCarrier ProteinsCell MembraneEukaryotic CellsHumansLipidsOrganellesCarrier ProteinsLipids

Identifiers

PMID21145454
PMCPMC3004474

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.