Evidence map›Paper›PMID 21145350›Full record

ReviewNeuroscience and biobehavioral reviews2011

The Adaptive Calibration Model of stress responsivity.

Marco Del Giudice, Bruce J Ellis, Elizabeth A Shirtcliff

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 520 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
520citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

520 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. A Systematic Review and Meta-Analytic Assessment of Unpredictability and Disordered Eating.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  10. Examining the impact of total sleep duration on daily affect among short-sleeping adolescents: an experimental study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2026
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  15. Oxytocin as regulator of stress and inflammation in aging.Neuroscience and biobehavioral reviews · 2026
    Review
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  18. Prenatal substance exposure and early childhood adversity: implications for child autonomic functioning at early school-age.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
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460 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marco Del GiudiceCenter for Cognitive Science, Department of Psychology, University of Turin, Via Po 14, 10123 Torino, Italy. marco.delgiudice@unito.it
Bruce J Ellis
Elizabeth A Shirtcliff

Funding

Stress Regulation and Psychopathology in AdolescentsK01MH077687 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI SHIRTCLIFF, ELIZABETH ANNE · 2007 to 2011
$654k
Biobehavioral Mechanisms for Severe Disruptive Behavior in Adolescent GirlsR21MH093675 · NIMH · UNIVERSITY OF NEW ORLEANS · PI SHIRTCLIFF, ELIZABETH ANNE · 2011 to 2012
$388k
NIMH NIH HHS K01 MH077687NIMH NIH HHS R21 MH093675
6 · The paper itself

Abstract

This paper presents the Adaptive Calibration Model (ACM), an evolutionary-developmental theory of individual differences in the functioning of the stress response system. The stress response system has three main biological functions: (1) to coordinate the organism's allostatic response to physical and psychosocial challenges; (2) to encode and filter information about the organism's social and physical environment, mediating the organism's openness to environmental inputs; and (3) to regulate the organism's physiology and behavior in a broad range of fitness-relevant areas including defensive behaviors, competitive risk-taking, learning, attachment, affiliation and reproductive functioning. The information encoded by the system during development feeds back on the long-term calibration of the system itself, resulting in adaptive patterns of responsivity and individual differences in behavior. Drawing on evolutionary life history theory, we build a model of the development of stress responsivity across life stages, describe four prototypical responsivity patterns, and discuss the emergence and meaning of sex differences. The ACM extends the theory of biological sensitivity to context (BSC) and provides an integrative framework for future research in the field.

Indexed as

Adaptation, BiologicalAdaptation, PsychologicalBiological EvolutionHuman DevelopmentModels, TheoreticalHumansIndividualitySex CharacteristicsStress, Psychological

Identifiers

PMID21145350
PMCPMC3068241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.