ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2010
Reducing uncertainty in managing respiratory tract infections in primary care.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Biomarkers as point-of-care tests to guide prescription of antibiotics in people with acute respiratory infections in primary care.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- Reducing antibiotic prescribing for children with respiratory tract infections in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013Pooled it
- Pooled it
- The Effectiveness of Small Group Education on Improving Antibiotic Prescribing in General Practice: A Mixed Methods Systematic Review.Antibiotics (Basel, Switzerland) · 2026Review
- Article
- The Introduction of the Global Traditional, Complementary, and Integrative Healthcare (TCIH) Research Agenda on Antimicrobial Resistance and Its Added Value to the WHO and the WHO/FAO/UNEP/WOAH 2023 Research Agendas on Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic Prescribing for Lower Respiratory Tract Infections and Community-Acquired Pneumonia: An Italian Pediatric Emergency Department's Real-Life Experience.Life (Basel, Switzerland) · 2023Article
- Potential Saving of Antibiotics for Respiratory Infections in Several European Countries: Insights from Market Research Data.Antibiotics (Basel, Switzerland) · 2023Article
- Prescribing antibiotics: the use of diagnostic tests in general practice. A register-based study.Scandinavian journal of primary health care · 2021Article
- Alternative approaches to managing respiratory tract infections: a survey of public perceptions.BJGP open · 2021Article
- Systematic Review on the Impact of Guidelines Adherence on Antibiotic Prescription in Respiratory Infections.Antibiotics (Basel, Switzerland) · 2020Review
- Relationship between microbiology of throat swab and clinical course among primary care patients with acute cough: a prospective cohort study.Family practice · 2020Article
- The Oxford Royal College of General Practitioners Clinical Informatics Digital Hub: Protocol to Develop Extended COVID-19 Surveillance and Trial Platforms.JMIR public health and surveillance · 2020Article
- Article
- Infectious disease burden and antibiotic prescribing in primary care in Israel.Annals of clinical microbiology and antimicrobials · 2018Article
- Which Point-of-Care Tests Would Be Most Beneficial to Add to Clinical Practice?: Findings From a Survey of 3 Family Medicine Clinics in the United States.Point of care · 2017Article
- Throat swabs in children with respiratory tract infection: associations with clinical presentation and potential targets for point-of-care testing.Family practice · 2017Article
- Microbiological point of care testing before antibiotic prescribing in primary care: considerable variations between practices.BMC family practice · 2017Article
- Observational
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory tract infections (RTIs) remain the commonest reason for acute consultations in primary care in resource-rich countries. Their spectrum and severity has changed from the time that antibiotics were discovered, largely from improvements in the socioeconomic determinants of health as well as vaccination. The benefits from antibiotic treatment for common RTIs have been shown to be largely overstated. Nevertheless, serious infections do occur. Currently, no clinical features or diagnostic test, alone or in combination, adequately determine diagnosis, aetiology, prognosis, or response to treatment. This narrative review focuses on emerging evidence aimed at helping clinicians reduce and manage uncertainty in treating RTIs. Consultation rate and prescribing rate trends are described, evidence of increasing rates of complications are discussed, and studies and the association with antibiotic prescribing are examined. Methods of improving diagnosis and identifying those patients who are at increased risk of complications from RTIs, using clinical scoring systems, biomarkers, and point of care tests are also discussed. The evidence for alternative management options for RTIs are summarised and the methods for changing public and clinicians' beliefs about antibiotics, including ways in which we can improve clinician-patient communication skills for management of RTIs, are described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.