Evidence map›Paper›PMID 21144126›Full record

ArticleGenetics research2011

MADS-box genes of maize: frequent targets of selection during domestication.

Qiong Zhao, Allison L Weber, Michael D McMullen, Katherine Guill, John Doebley

Open access · bronzeAbstract read
In one paragraph

Article in Genetics research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

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  5. Overexpression ofProceedings of the National Academy of Sciences of the United States of America · 2019
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  19. Reshaping of the maize transcriptome by domestication.Proceedings of the National Academy of Sciences of the United States of America · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Qiong ZhaoLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Allison L Weber
Michael D McMullen
Katherine Guill
John Doebley
University of Wisconsin–Madison · USAgricultural Research Service · USUniversity of Missouri · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
MOLECULAR GENETICS OF VARIATION FOR COMPLEX TRAITSR01GM058816 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI DOEBLEY, JOHN F · 1999 to 2007
$1.6M
NIGMS NIH HHS R01 GM058816NIGMS NIH HHS T32 GM007133
6 · The paper itself

Abstract

MADS-box genes encode transcription factors that are key regulators of plant inflorescence and flower development. We examined DNA sequence variation in 32 maize MADS-box genes and 32 randomly chosen maize loci and investigated their involvement in maize domestication and improvement. Using neutrality tests and a test based on coalescent simulation of a bottleneck model, we identified eight MADS-box genes as putative targets of the artificial selection associated with domestication. According to neutrality tests, one additional MADS-box gene appears to have been under selection during modern agricultural improvement of maize. For random loci, two genes were indicated as targets of selection during domestication and four additional genes were indicated to be candidate-selected loci for maize improvement. These results suggest that MADS-box genes were more frequent targets of selection during domestication than genes chosen at random from the genome.

Indexed as

Genes, PlantGenetic VariationGenome, PlantPlant ProteinsSelection, GeneticTranscription FactorsZea maysPlant ProteinsTranscription Factors

Identifiers

PMID21144126
PMCPMC3474543
OpenAlexW2096989423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.