Evidence map›Paper›PMID 21144049›Full record

ArticleBMC cancer2010

Potential drug interactions and duplicate prescriptions among ambulatory cancer patients: a prevalence study using an advanced screening method.

Roelof W F van Leeuwen, Eleonora L Swart, Frits A Boom, Martin S Schuitenmaker, Jacqueline G Hugtenburg

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

  1. Observational
  2. Article
  3. Observational
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  5. Sedatives and analgesics are major contributors to potentially inappropriate duplicate prescriptions in geriatric psychiatry.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2023
    Article
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  10. Polypharmacy in the terminal stage of cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Roelof W F van LeeuwenDepartment of Clinical Pharmacology and Pharmacy, VU University medical center, Amsterdam, The Netherlands.
Eleonora L Swart
Frits A Boom
Martin S Schuitenmaker
Jacqueline G Hugtenburg
Amsterdam UMC Location VUmc · NLZaans Medisch Centrum · NLEMGO Institute for Health and Care Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. Drug interactions and duplicate prescriptions between anti-cancer drugs or interactions with medication to treat comorbidity can reinforce or intensify side-effects.The aim of the present study is to gain more insight into the prevalence of drug interactions and duplicate prescriptions among patients being treated in the outpatient day care departments for oncology and hematological illnesses. For the first time the prevalence of drug interactions with OTC-drugs in cancer patients will be studied. Possible risk factors for the occurrence of these drug-related problems will also be studied. METHODS/

designA multicenter cross-sectional observational study of the epidemiology of drug interactions and duplicate prescriptions is performed among all oncology and hemato-oncology patients treated with systemic anti-cancer drugs at the oncology and hematology outpatient day care department of the VU University medical center and the Zaans Medical Center. DISCUSSION: In this article the prevalence of potential drug interactions in outpatient day-care patients treated with anti-cancer agents is studied using a novel more extensive screening method. If this study shows a high prevalence of drug interactions clinical pharmacists and oncologists must collaborate to develop a pharmaceutical screening programme, including an automated electronic warning system, to support drug prescribing for ambulatory cancer patient. This programme could minimize the occurrence of drug related problems such as drug interactions and duplicate prescriptions, thereby increasing quality of life.

trial registrationThis study is registered, number NTR2238.

Indexed as

Research DesignAcademic Medical CentersAmbulatory CareAntineoplastic AgentsCross-Sectional StudiesDrug InteractionsDrug PrescriptionsHumansMedication ErrorsMedication Systems, HospitalNeoplasmsNetherlandsNonprescription DrugsPharmacy Service, HospitalPolypharmacyPractice Patterns, Physicians'Antineoplastic AgentsNonprescription Drugs

Identifiers

PMID21144049
PMCPMC3013087
OpenAlexW2120767567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.