ReviewCritical care (London, England)2010
Clinical review: the ABC of weaning failure--a structured approach.
Review in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03608332 (Diaphragmatic Ultrasound as a Guide Tool During Weaning From Mechanical Ventilation), which is not on this map. Cited by 96 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diaphragmatic Ultrasound as a Guide Tool During Weaning From Mechanical Ventilation (Randomized Controlled Trial)
Who cites it
96 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Efficacy of inspiratory muscle training on weaning success in mechanically ventilated ICU patients: a systematic review and network meta-analysis of randomized controlled trials.BMC pulmonary medicine · 2026Pooled it
- Effect of proportional assist ventilation plus versus pressure support ventilation on successful weaning in critically ill adults: a systematic review, meta-analysis, and trial sequential analysis.Frontiers in medicine · 2026Pooled it
- Physiological Effects of High-Flow Tracheal Oxygen in Tracheostomized Patients Weaning From Mechanical Ventilation.Respiratory care · 2024Pooled it
- Accuracy of respiratory muscle assessments to predict weaning outcomes: a systematic review and comparative meta-analysis.Critical care (London, England) · 2024Pooled it
- Efficacy of Physiotherapy Interventions on Weaning in Mechanically Ventilated Critically Ill Patients: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Pooled it
- A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study.Critical care (London, England) · 2026Trial
- Trial
- A randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation.International journal of chronic obstructive pulmonary disease · 2016Trial
- Can donepezil facilitate weaning from mechanical ventilation in difficult to wean patients? An interventional pilot study.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2015Trial
- Reintubation in the ICU: A Prospective Observational Study of Its Impact on Recovery Outcomes and Mortality.Cureus · 2026Article
- Resuscitation preference conversation typologies: a constructivist grounded theory study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Machine learning models predicting extubation success in mechanically ventilated patients: a systematic review and meta-analysis.Intensive care medicine experimental · 2026Review
- Integrated Multimodal Critical Care Ultrasound for Mechanism-Based Prediction of Weaning Failure: A Prospective Pilot Study.Journal of clinical medicine · 2026Article
- Integrated comprehensive assessment for predicting weaning success in difficult-to-wean critically ill patients: the WEAN-US study.Critical care (London, England) · 2026Observational
- Weaning from invasive ventilation with levosimendan (WEANLESS): study protocol for a multicentre randomised clinical trial.BMJ open · 2026Article
- Predictive value of resting energy expenditure and oxygen consumption of breathing for ventilator weaning in surgical intensive care patients in Viet Nam: a cross-sectional study.Acute and critical care · 2026Article
- Mechanical power normalized to dynamic lung compliance as a predictor of weaning and prognosis in mechanically ventilated patients: a retrospective cohort study.BMC anesthesiology · 2025Observational
- ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Lung electrical impedance tomography during positioning, weaning and chest physiotherapy in mechanically ventilated critically ill patients: a narrative review.Annals of intensive care · 2025Review
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE') for the assessment and treatment of difficult-to-wean patients. Earlier recognition of the underlying causes may expedite weaning from mechanical ventilation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.