Trial reportJournal of the American Geriatrics Society2010
Are changes in leg power responsible for clinically meaningful improvements in mobility in older adults?
Trial report in Journal of the American Geriatrics Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of power training to improve physical function in individuals diagnosed with frailty and chronic disease: A meta-analysis.Physiological reports · 2022Pooled it
- Skeletal muscle changes following stroke: a systematic review and comparison to healthy individuals.Topics in stroke rehabilitation · 2017Pooled it
- Physical Activity Intervention Effects on Physical Function Among Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.Journal of aging and physical activity · 2017Pooled it
- Ageing, Muscle Power and Physical Function: A Systematic Review and Implications for Pragmatic Training Interventions.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.Rheumatology international · 2026Trial
- The Otago Exercise Program With or Without Motivational Interviewing for Community-Dwelling Older Adults: A 12-Month Follow-Up of a Randomized, Controlled Trial.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2021Trial
- Exercise-based pre-habilitation is feasible and effective in radical cystectomy pathways-secondary results from a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Trial
- Trial
- Are resistance and aerobic exercise training equally effective at improving knee muscle strength and balance in older women?Archives of gerontology and geriatricsTrial
- High-velocity resistance training improves the force-velocity profile in middle-aged and older adults.GeroScience · 2026Article
- Multidimensional associations of physical performance, balance, wellness and daily activities with frailty in older adults with coexisting frailty and diabetes.Journal of clinical nursing · 2026Article
- Initial contractions of a single-load fatiguing exercise provide a valid assessment of age-related differences in peak power.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Early-Phase and Cross-Education Adaptations Following Very Short-Term Unilateral Isokinetic Forearm Extension and Flexion Training in Untrained Women.Muscles (Basel, Switzerland) · 2026Article
- Veterans' Motivation, Preference, and Feedback After Completing a Novel Physical Therapy Treatment.Journal of aging and physical activity · 2025Article
- Muscle power predicts frailty and other adverse events across different settings.The journal of nutrition, health & aging · 2025Article
- Evaluating the Agreement and Associations with Physical Function Between Equation- and Linear Position Transducer-Estimated Sit-to-Stand Muscle Power in Aging Adults.Healthcare (Basel, Switzerland) · 2025Article
- Sit-to-Stand Power Is a Stronger Predictor of Gait Speed than Knee Extension Strength.Journal of functional morphology and kinesiology · 2024Article
- Defining Clinically Meaningful Cut Points for Leg Power Impairment Using Physical Performance in Older Adults: A Secondary Analysis From Boston RISE.Archives of physical medicine and rehabilitation · 2024Observational
- Review
- Effects of high-intensity interval training on lean mass, strength, and power of the lower limbs in healthy old and young people.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesFrom among physiological attributes commonly targeted in rehabilitation, to identify those in which changes led to clinically meaningful differences (CMDs) in mobility outcomes.
designSecondary analysis of data collected for a randomized controlled trial of exercise using binary outcomes defined by recording a large CMD (Short Physical Performance Battery (SPPB)=1 unit; gait speed (GS)=0.1 m/s). Iterative models were performed to evaluate possible confounding between physiological variables and relevant covariates.
settingOutpatient rehabilitation centers.
participantsCommunity-dwelling mobility-limited older adults (n=116) participating in a 16-week randomized controlled trial of two modes of exercise. MEASUREMENTS: Physiological measures included leg power, leg strength, balance as measured according to the Performance-Oriented Mobility Assessment (POMA), and rate pressure product at the maximal stage of an exercise tolerance test. Outcomes included GS and SPPB. Leg power and leg strength were measured using computerized pneumatic strength training equipment and recorded in Watts and Newtons, respectively.
resultsParticipants were 68% female, had a mean age of 75.2, a mean of 5.5 chronic conditions, and a baseline mean SPPB score of 8.7. After controlling for age, site, group assignment, and baseline outcome values, leg power was the only attribute in which changes were significantly associated with a large CMD in SPPB (odds ratio (OR)=1.48, 95% confidence interval (CI)=1.09-2.02) and GS (OR=1.31, 95% CI=1.01-1.70).
conclusionImprovements in leg power, independent of strength, appear to make an important contribution to clinically meaningful improvements in SPPB and GS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.