Evidence map›Paper›PMID 21138864›Full record

ReviewClinical cancer research : an official journal of the American Association for Cancer Research2010

New strategies in peripheral T-cell lymphoma: understanding tumor biology and developing novel therapies.

Kieron Dunleavy, Richard L Piekarz, Jasmine Zain, John E Janik, Wyndham H Wilson, Owen A O'Connor, Susan E Bates

Open access · bronzeAbstract readEvaluation StudyReview
In one paragraph

Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Outcomes of GDPT (gemcitabine, cisplatin, prednisone, thalidomide)Therapeutic advances in medical oncology · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. NK/T-cell lymphomas in children.Best practice & research. Clinical haematology · 2013
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kieron DunleavyCenter for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892–1868, USA. dunleavk@mail.nih.gov
Richard L Piekarz
Jasmine Zain
John E Janik
Wyndham H Wilson
Owen A O'Connor
Susan E Bates
New York University · USCenter for Cancer Research · USNational Cancer Institute · USNYU Langone Health · US

Funding

Translational Studies of the Histone Deacetylase Inhibitor RomidepsinZIABC010621 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BATES, SUSAN · 2009 to 2015
$6.2M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Peripheral T-cell lymphomas (PTCL) constitute a group of heterogeneous diseases that are uncommon, representing, in Western countries, only approximately 10% of all non-Hodgkin lymphomas. They are typically associated with a poor prognosis compared with their B-cell counterparts and are much less well understood with respect to tumor biology, owing to their rarity and biologic heterogeneity, and to the fact that characteristic cytogenetic abnormalities are few compared with B-cell lymphomas. Although the outcome for patients with anaplastic large cell lymphoma (ALCL), particularly anaplastic lymphoma kinase (ALK)-positive ALCL, is good, other types of PTCLs are associated with a poor prognosis, even with aggressive anthracycline-based chemotherapy. In this respect, there is a need for new approaches in these diseases, and this review focuses on and explores recent experience with novel therapies in PTCL.

Indexed as

AnimalsAntineoplastic AgentsCell BiologyComprehensionDrug DiscoveryGene Expression ProfilingHumansLymphoma, T-Cell, PeripheralMolecular Targeted TherapyTherapies, InvestigationalAntineoplastic Agents

Identifiers

PMID21138864
PMCPMC3058794
OpenAlexW2163263870

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.