Evidence map›Paper›PMID 21138274›Full record

ArticleBioconjugate chemistry2011

A universal protocol for photochemical covalent immobilization of intact carbohydrates for the preparation of carbohydrate microarrays.

Huibin Wang, Yiming Zhang, Xun Yuan, Yi Chen, Mingdi Yan

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Analysis of the surface density and reactivity of perfluorophenylazide and the impact on ligand immobilization.Journal of vacuum science & technology. A, Vacuum, surfaces, and films : an official journal of the American Vacuum Society · 2015
    Article
  5. Article
  6. Article
  7. Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity.Integrative biology : quantitative biosciences from nano to macro · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huibin WangKey Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Yiming Zhang
Xun Yuan
Yi Chen
Mingdi Yan

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
Surface Chemistry for Immobilization of Ultrathin FilmsR15GM066279 · NIGMS · PORTLAND STATE UNIVERSITY · PI YAN, MINGDI · 2005 to 2008
$410k
NIGMS NIH HHS R01 GM080295NIGMS NIH HHS R01GM080295NIGMS NIH HHS R15 GM066279NIGMS NIH HHS R15GM066279
6 · The paper itself

Abstract

A universal photochemical method has been established for the immobilization of intact carbohydrates and their analogues, and for the fabrication of carbohydrate microarrays. The method features the use of perfluorophenyl azide (PFPA)-modified substrates and the photochemical reaction of surface azido groups with printed carbohydrates. Various aldoses, ketoses, nonreducing sugars such as alditols, and their derivatives can be directly arrayed on the PFPA-modified chips. The lectin-recognition ability of arrayed mannose, glucose, and their oligo- and polysaccharides were confirmed using surface plasmon resonance imaging and laser-induced fluorescence imaging.

Indexed as

Photochemical ProcessesAzidesCarbohydrate MetabolismCarbohydratesHydrocarbons, FluorinatedLectinsLightMicroarray AnalysisSurface PropertiesAzidesCarbohydratesHydrocarbons, FluorinatedLectinsperfluorophenyl azide

Identifiers

PMID21138274
PMCPMC3023832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.