ReviewMedizinische Klinik (Munich, Germany : 1983)2010
[Immunosenescence and vaccinations in the elderly].
Review in Medizinische Klinik (Munich, Germany : 1983), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- [Immunizing is not only a children's matter! : Why vaccinations are also important for adults].Wiener medizinische Wochenschrift (1946) · 2019Review
- Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans.Age (Dordrecht, Netherlands) · 2013Article
- [Severe pneumococcal infections in the elderly - preventable by vaccination].Zeitschrift fur Gerontologie und Geriatrie · 2013Article
- Chrononutrition against oxidative stress in aging.Oxidative medicine and cellular longevity · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With increasing age, infection-induced morbidity and mortality rises. At the same time, the protective capacity of the immune system declines. This phenomenon is known as immunosenescence. It concerns all parts of the immune system and leads to a decline of cellular and humoral immune defense. As a consequence, the ability to resist infections and the immune response to vaccinations could be impaired. In order to protect senior citizens effectively against infections with dangerous pathogens like influenza viruses or pneumococci, new immunisation strategies, e.g. with shortened intervals between vaccinations, new vaccines or new vaccination techniques are required. Intradermal vaccines seem to be a promising approach, for instance. At the same time the acceptance of vaccination ought to be increased in the senior age group. Physicians, especially general practitioners play an important role because of their decisive effect on the willingness of the population to get vaccinated.
Indexed as
Identifiers
21136238What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.