Evidence map›Paper›PMID 21134576›Full record

GuidelineThe Journal of allergy and clinical immunology2010

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.

NIAID-Sponsored Expert Panel, Joshua A Boyce, Amal Assa'ad, A Wesley Burks, Stacie M Jones, Hugh A Sampson, Robert A Wood, Marshall Plaut, Susan F Cooper, Matthew J Fenton and 20 more

3 registry-linked trialsOpen access · bronzeAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 577 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
577citing papers in PubMed, 7 pooled it
30.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03456479 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Diagnosis of Cow's Milk Protein Allergy Among Infants and Children in Assuit University

TypeinterventionalSponsorAssiut UniversityRan2019 to 2020Enrolled30ConditionsCow Milk AllergyArmsskin prick test - specific serum IgE
NCT05960045 nacompletednot on this mapstarted 2024, after this paper: background citation

Testing Tolerance in Cow Milk Protein Allergy Patients: Milk Ladder or Direct Milk Administration?

TypeinterventionalSponsorAin Shams UniversityRan2024 to 2025Enrolled116ConditionsCow Milk Allergy, ToleranceArmsDirect Milk antigen reintroduction, Milk ladder
NCT07750236 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Watching Cartoons and Using a Stress Ball on Fear, Anxiety, Pain, and Satisfaction During Allergy Testing in Children

TypeinterventionalSponsorTarsus UniversityRan2026 to 2027Enrolled90ConditionsChild Allergy, Anxiety, Fear, PainArmscartoon-watching group, stress ball group
3 · Its place in the literature

Who cites it

577 citing papers in PubMed, 7 syntheses or guidelines pooled it, 1,243 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2022
    Pooled it
  7. Frontiers in pediatrics · 2022
    Pooled it
  8. Trial
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. [How I treat anaphylaxis in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

517 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

NIAID-Sponsored Expert PanelDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.
Joshua A Boyce
Amal Assa'ad
A Wesley Burks
Stacie M Jones
Hugh A Sampson
Robert A Wood
Marshall Plaut
Susan F Cooper
Matthew J Fenton
S Hasan Arshad
Sami L Bahna
Lisa A Beck
Carol Byrd-Bredbenner
Carlos A Camargo
Lawrence Eichenfield
Glenn T Furuta
Jon M Hanifin
Carol Jones
Monica Kraft
Bruce D Levy
Phil Lieberman
Stefano Luccioli
Kathleen M McCall
Lynda C Schneider
Ronald A Simon
F Estelle R Simons
Stephen J Teach
Barbara P Yawn
Julie M Schwaninger

Funding

Intramural NIH HHS NIH0012222082PHS HHS NIH0012222082
6 · The paper itself

Abstract

Food allergy is an important public health problem that affects children and adults and may be increasing in prevalence. Despite the risk of severe allergic reactions and even death, there is no current treatment for food allergy: the disease can only be managed by allergen avoidance or treatment of symptoms. The diagnosis and management of food allergy also may vary from one clinical practice setting to another. Finally, because patients frequently confuse nonallergic food reactions, such as food intolerance, with food allergies, there is an unfounded belief among the public that food allergy prevalence is higher than it truly is. In response to these concerns, the National Institute of Allergy and Infectious Diseases, working with 34 professional organizations, federal agencies, and patient advocacy groups, led the development of clinical guidelines for the diagnosis and management of food allergy. These Guidelines are intended for use by a wide variety of health care professionals, including family practice physicians, clinical specialists, and nurse practitioners. The Guidelines include a consensus definition for food allergy, discuss comorbid conditions often associated with food allergy, and focus on both IgE-mediated and non-IgE-mediated reactions to food. Topics addressed include the epidemiology, natural history, diagnosis, and management of food allergy, as well as the management of severe symptoms and anaphylaxis. These Guidelines provide 43 concise clinical recommendations and additional guidance on points of current controversy in patient management. They also identify gaps in the current scientific knowledge to be addressed through future research.

Indexed as

AdultChildDiagnosis, DifferentialFood HypersensitivityHumans

Identifiers

PMID21134576
PMCPMC4241964
OpenAlexW3142188131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.