Evidence map›Paper›PMID 21133727›Full record

ReviewLeukemia & lymphoma2011

Mantle cell lymphoma: report of the 2010 Mantle Cell Lymphoma Consortium Workshop.

Michael E Williams, Joseph M Connors, Martin H Dreyling, Randy D Gascoyne, Brad S Kahl, John P Leonard, Oliver W Press, Wyndham H Wilson

Open access · greenAbstract readReview
In one paragraph

Review in Leukemia & lymphoma, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Nanopharmacology in translational hematology and oncology.International journal of nanomedicine · 2014
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Michael E WilliamsUniversity of Virginia School of Medicine, Charlottesville, VA, USA. mew4p@virginia.edu
Joseph M Connors
Martin H Dreyling
Randy D Gascoyne
Brad S Kahl
John P Leonard
Oliver W Press
Wyndham H Wilson
BC Cancer Agency · CACornell University · USFred Hutch Cancer Center · USMünchen Klinik · DENational Cancer Institute · USUniversity of Virginia · USUniversity of Wisconsin–Madison · US

Funding

Therapeutic Strategies and Molecular Correlates in Aggressive B-cell LymphomasZIASC006741 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI WILSON, WYNDHAM H · 2009 to 2025
$10.4M
Targeted treatment of B-cell LymphomaZIABC011354 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, WYNDHAM H · 2010 to 2025
$4.6M
Phase III Study of R-CHOP v DA-EPOCH-R with microarrayZIABC010728 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, WYNDHAM H · 2009 to 2021
$1.4M
Phase III study of BCL-family inhibitors in lymphomaZIABC010716 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, WYNDHAM H · 2009 to 2013
$1.1M
Phase II study of flavopiridol in mantle cell lymphoma and DLBCLZIABC010715 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, WYNDHAM H · 2009 to 2013
$689k
Phase II study of flavopiridol in mantle cell lymphoma and DLBCLZ01BC010715 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WILSON, WYNDHAM H · 2006 to 2008
$424k
Intramural NIH HHS Z01 BC010715
6 · The paper itself

Abstract

Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma typically characterized by cyclin D1 overexpression as result of the t(11;14) translocation. MCL is biologically and clinically heterogeneous and frequently involves extranodal dissemination. Although MCL is incurable with current therapies, with the exception of allogeneic stem cell transplant, recent advances are improving long-term outcomes in MCL. Intensive research has continued to focus on elucidating biological mechanisms of MCL, identifying new molecular targets, and optimizing existing therapies. Most recently, researchers have begun focusing on new areas such as epigenetics and microRNAs and their potential applications to MCL therapy. Advances across a broad spectrum of MCL research were presented at a recent MCL Workshop. This report provides an overview of the scientific highlights from the meeting and a framework for future research.

Indexed as

EpigenomicsCongresses as TopicHumansLymphoma, Mantle-CellPrognosis

Identifiers

PMID21133727
PMCPMC7357185
OpenAlexW2616989782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.