Evidence map›Paper›PMID 21132416›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2011

The multiphase optimization strategy for engineering effective tobacco use interventions.

Linda M Collins, Timothy B Baker, Robin J Mermelstein, Megan E Piper, Douglas E Jorenby, Stevens S Smith, Bruce A Christiansen, Tanya R Schlam, Jessica W Cook, Michael C Fiore

5 registry-linked trialsAbstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 182 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03254940 nacompletednot on this mapstarted 2018, after this paper: background citation

Charge: Optimizing a Standalone Text Messaging-Based Weight Loss Intervention

TypeinterventionalSponsorDuke UniversityRan2018 to 2023Enrolled534ConditionsWeight Loss, ObesityArmsCharge
NCT05375162 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for Adolescent and Young Adult Cancer Survivors

TypeinterventionalSponsorNorthwestern UniversityRan2023 to 2026Enrolled304ConditionsCancerArmsCore Intervention, E-Coach, General Mindfulness Training, MVPA-Specific Mindfulness Training, Buddy
NCT05931874 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Fit2ThriveMIND: Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors

TypeinterventionalSponsorNorthwestern UniversityRan2024 to 2027Enrolled304ConditionsBreast CancerArmsCore Intervention, E-Coach, Buddy, General Mindfulness Training, MVPA-Specific Mindfulness Training
NCT06358339 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Tailored Evidence-based Enhancements in Mental Health-Gamified and Individualized Follow-Up Treatment for Suicide (TEEM-GIFTS) : Implementing a Gamified mHealth Intervention to Reduce Post-Discharge Suicide Risk in Patients With Mental Disorders Using Multiphase Optimization Strategy (MOST)

TypeinterventionalSponsorShenzhen Kangning HospitalRan2025 to 2027Enrolled640ConditionsSuicideArmsTEEM
NCT07067151 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Use of Noninvasive Wearables Biomonitoring to Detect Pre-Smoking, Smoking, And Post-Smoking Stages: An Observational Laboratory Study

TypeobservationalSponsorNational Institute on Minority Health and Health Disparities (NIMHD)Ran2026 to 2028Enrolled30ConditionsSmoking
3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linda M CollinsThe Pennsylvania State University, University Park, USA.
Timothy B Baker
Robin J Mermelstein
Megan E Piper
Douglas E Jorenby
Stevens S Smith
Bruce A Christiansen
Tanya R Schlam
Jessica W Cook
Michael C Fiore

Funding

INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
THE REFINEMENT &APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCESP50DA010075 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI MURPHY, SUSAN A · 1996 to 2014
$24.5M
Methods CoreP50CA143188 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B, COLLINS, LINDA M · 2009 to 2013
$10.5M
Dynamical System /Related Engineering Approach /Improving Behavioral InterventionR21DA024266 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI COLLINS, LINDA M, RIVERA, DANIEL E · 2007 to 2010
$1.1M
Training in Translational Tobacco ScienceK05CA139871 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B · 2008 to 2012
$850k
Influence of Nicotine on Positive and Negative Affect in Smokers with PTSDK08DA021311 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI COOK, JESSICA MEGAN · 2007 to 2011
$827k
NCI NIH HHS 1K05CA139871NCI NIH HHS 9P50CA143188-11NCI NIH HHS K05 CA139871NCI NIH HHS P50 CA143188NCRR NIH HHS 1UL1RR025011NCRR NIH HHS UL1 RR025011NIDA NIH HHS K08 DA021311NIDA NIH HHS K08DA021311NIDA NIH HHS P50 DA010075NIDA NIH HHS P50DA10075NIDA NIH HHS R21 DA024266
6 · The paper itself

Abstract

The multiphase optimization strategy (MOST) is a new methodological approach for building, optimizing, and evaluating multicomponent interventions. Conceptually rooted in engineering, MOST emphasizes efficiency and careful management of resources to move intervention science forward steadily and incrementally. MOST can be used to guide the evaluation of research evidence, develop an optimal intervention (the best set of intervention components), and enhance the translation of research findings, particularly type II translation. This article uses an ongoing study to illustrate the application of MOST in the evaluation of diverse intervention components derived from the phase-based framework reviewed in the companion article by Baker et al. (Ann Behav Med, in press, 2011). The article also discusses considerations, challenges, and potential benefits associated with using MOST and similar principled approaches to improving intervention efficacy, effectiveness, and cost-effectiveness. The applicability of this methodology may extend beyond smoking cessation to the development of behavioral interventions for other chronic health challenges.

Indexed as

Behavior TherapyCost-Benefit AnalysisEngineeringHumansModels, TheoreticalOutcome Assessment, Health CareProgram DevelopmentProgram EvaluationResearch DesignSmoking CessationTobacco Use DisorderTranslational Research, Biomedical

Identifiers

PMID21132416
PMCPMC3053423

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.