Evidence map›Paper›PMID 21132086›Full record

ArticleAging and disease2010

Modern Biological Theories of Aging.

Kunlin Jin

Abstract read
In one paragraph

Article in Aging and disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Metabolomic Profiling ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. A novel information-theoretic approach reveals loss of effective biomolecular communication in aging muscle cells.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Sex as a Determinant of Age-Related Changes in the Brain.International journal of molecular sciences · 2024
    Review
  20. Article

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kunlin JinAging and Disease, 8001 Redwood, Blvd. Novato, California 94945, USA.

Funding

Aging and NeurogenesisR01AG021980 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI JIN, KUNLIN · 2003 to 2014
$3.9M
Functional contribution of neural stem cells in strokeR01NS057186 · NINDS · BUCK INSTITUTE FOR RESEARCH ON AGING · PI JIN, KUNLIN · 2009 to 2010
$970k
NIA NIH HHS R01 AG021980NINDS NIH HHS R01 NS057186
6 · The paper itself

Abstract

Despite recent advances in molecular biology and genetics, the mysteries that control human lifespan are yet to be unraveled. Many theories, which fall into two main categories: programmed and error theories, have been proposed to explain the process of aging, but neither of them appears to be fully satisfactory. These theories may interact with each other in a complex way. By understanding and testing the existing and new aging theories, it may be possible to promote successful aging.

Identifiers

PMID21132086
PMCPMC2995895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.