Evidence map›Paper›PMID 21132025›Full record

Trial reportBone marrow transplantation2011

Effects of an outpatient physical exercise program on hematopoietic stem-cell transplantation recipients: a randomized clinical trial.

R H Knols, E D de Bruin, D Uebelhart, G Aufdemkampe, U Schanz, F Stenner-Liewen, F Hitz, C Taverna, N K Aaronson

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03448627 completednot on this mapstarted 2012, after this paper: background citation

Physiological Responses to Maximal Exercise Capacity and Muscle Strength in Survived Hematopoietic Stem Cell Transplantation Recipients

TypeobservationalSponsorGazi UniversityRan2012 to 2017Enrolled122ConditionsStem Cell Transplantation
NCT06907004 completednot on this mapstarted 2023, after this paper: background citation

Developing a Exercise Program for Patients Undergoing Hematopoietic Stem Cell Transplantation: An Action Research Approach.

TypeobservationalSponsorChimei Medical CenterRan2023 to 2023Enrolled24ConditionsHematopoietic Stem Cell Transplantation
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R H KnolsDepartment of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland. ruud.knols@usz.ch
E D de Bruin
D Uebelhart
G Aufdemkampe
U Schanz
F Stenner-Liewen
F Hitz
C Taverna
N K Aaronson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients who undergo hematopoietic SCT (HSCT) often experience physical and psychological problems, even long after treatment has been completed. This study was performed to evaluate the effects of a 12-week outpatient physical exercise (PE) program, incorporating aerobic and strength exercises, as compared with a usual care control condition on patients' physical performance and psychosocial well-being. Patients who had completed HSCT up to 6 months earlier were randomly assigned to a supervised PE program (n=64) or a usual care control group (n=67). Primary outcomes were quantified physical performance and self-reported physical functioning. Secondary outcomes were body composition measurement, quantified walking activity and patient-reported outcomes (physical activity, fatigue and health-related quality of life). Assessments were at baseline, immediately after program completion and at 3-month follow-up. Significant intervention effects were observed at both posttreatment and follow-up on physical performance measures. No other outcomes yielded statistically significant group differences. PE should be considered in the management of HSCT recipients to improve physical performance after discharge from the hospital. Further research is needed to determine how the program can be enhanced so that improved physical performance also translates into improved physical and psychosocial functioning in daily life.

Indexed as

Exercise TherapyAdolescentAdultAgedFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedOutpatientsPhysical FitnessProspective StudiesQuality of LifeYoung Adult

Identifiers

PMID21132025

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.