Evidence map›Paper›PMID 21131437›Full record

ArticleEukaryotic cell2011

The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death.

Bárbara de Castro Pimentel Figueiredo, Patrícia Alves de Castro, Taísa Magnani Dinamarco, Maria Helena S Goldman, Gustavo Henrique Goldman

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. mSphere · 2023
    Article
  2. TheG3 (Bethesda, Md.) · 2018
    Article
  3. Regulated Forms of Cell Death in Fungi.Frontiers in microbiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bárbara de Castro Pimentel FigueiredoFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Av. do Café S/N, CEP 14040-903, Ribeirão Preto, São Paulo, Brazil.
Patrícia Alves de Castro
Taísa Magnani Dinamarco
Maria Helena S Goldman
Gustavo Henrique Goldman
Universidade de São Paulo · BRLaboratório Nacional de Ciência e Tecnologia do Bioetanol · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon apoptosis induction, translocation of mammalian mitochondrial endonuclease G (EndoG) to the nucleus coincides with large-scale DNA fragmentation. Here, we describe for the first time a homologue of EndoG in filamentous fungi by investigating if the Aspergillus nidulans homologue of the EndoG gene, named nucA(EndoG), is being activated during farnesol-induced cell death. Our results suggest that NucA is not involved in cell death, but it plays a role in the DNA-damaging response in A. nidulans.

Indexed as

ApoptosisAspergillus nidulansDNA DamageEndodeoxyribonucleasesFarnesolFungal ProteinsGene DeletionGene Expression Regulation, FungalMitochondrial ProteinsPhenotypeRecombinant Fusion ProteinsUp-RegulationEndodeoxyribonucleasesFarnesolFungal ProteinsMitochondrial ProteinsRecombinant Fusion Proteins

Identifiers

PMID21131437
PMCPMC3067401
OpenAlexW2139414430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.