ArticleEukaryotic cell2011
A single mating-type locus composed of homeodomain genes promotes nuclear migration and heterokaryosis in the white-rot fungus Phanerochaete chrysosporium.
Article in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 54 citations in OpenAlex.
- Loss of Ku70 promotes mononucleate conidiation and homologous recombination inApplied and environmental microbiology · 2026Article
- The complex evolution and genomic dynamics of mating-type loci in Cryptococcus and Kwoniella.PLoS biology · 2025Article
- Tracing the evolution and genomic dynamics of mating-type loci inbioRxiv : the preprint server for biology · 2025Article
- Regulatory functions of homeobox domain transcription factors in fungi.Applied and environmental microbiology · 2024Review
- Lessons on fruiting body morphogenesis from genomes and transcriptomes ofStudies in mycology · 2023Article
- Structural Analysis of theJournal of fungi (Basel, Switzerland) · 2023Article
- Ontogenetic Variation in Macrocyclic and Hemicyclic Poplar Rust Fungi.International journal of molecular sciences · 2022Article
- Large-scale fungal strain sequencing unravels the molecular diversity in mating loci maintained by long-term balancing selection.PLoS genetics · 2022Article
- Review
- Competing sexual-asexual generic names in Agaricomycotina (Basidiomycota) with recommendations for use.IMA fungus · 2021Article
- Article
- What Role Might Non-Mating Receptors Play inJournal of fungi (Basel, Switzerland) · 2021Article
- Analysis of the Genome Sequence of Strain GiC-126 ofMycobiology · 2021Article
- Identification, characterization and expression ofMycoscience · 2021Article
- Genome Sequence Analysis ofJournal of fungi (Basel, Switzerland) · 2020Article
- Possible mechanisms of control of Fusarium wilt of cut chrysanthemum by Phanerochaete chrysosporium in continuous cropping fields: A case study.Scientific reports · 2017Article
- Fungal Sex: The Basidiomycota.Microbiology spectrum · 2017Review
- The good, the bad and the tasty: The many roles of mushrooms.Studies in mycology · 2016Article
- Fruiting Body Formation in Volvariella volvacea Can Occur Independently of Its MAT-A-Controlled Bipolar Mating System, Enabling Homothallic and Heterothallic Life Cycles.G3 (Bethesda, Md.) · 2016Article
- The cacao pathogen Moniliophthora roreri (Marasmiaceae) possesses biallelic A and B mating loci but reproduces clonally.Heredity · 2016Article
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The white-rot basidiomycete fungus Phanerochaete chrysosporium (Agaricomycetes) is a model species that produces potent wood-degrading enzymes. The mating system of the species has been difficult to characterize due to its cryptic fruiting habit and lack of clamp connections in the heterokaryotic phase. By exploiting the draft genome sequence, we reevaluated the mating system of P. chrysosporium by studying the inheritance and segregation of putative mating-type gene homologues, the homeodomain transcription factor genes (MAT-A) and the pheromone receptors (MAT-B). A pattern of mating incompatibility and fructification consistent with a bipolar system with a single MAT locus was observed, but the rejection response was much weaker than that seen in other agaricomycete species, leading to stable heterokaryons with identical MAT alleles. The homeodomain genes appear to comprise the single MAT locus because they are heterozygous in wild strains and hyperpolymorphic at the DNA sequence level and promote aspects of sexual reproduction, such as nuclear migration, heterokaryon stability, and basidiospore formation. The pheromone receptor loci that might constitute a MAT-B locus, as in many other Agaricomycetes, are not linked to the MAT-A locus and display low levels of polymorphism. This observation is inconsistent with a bipolar mating system that includes pheromones and pheromone receptors as mating-type determinants. The partial uncoupling of nuclear migration and mating incompatibility in this species may be predicted to lead to parasexual recombination and may have contributed to the homothallic behavior observed in previous studies.
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