ArticleEukaryotic cell2011
Interaction between the Candida albicans high-osmolarity glycerol (HOG) pathway and the response to human beta-defensins 2 and 3.
Article in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 46 citations in OpenAlex.
- Vitamin D-AMP axis in host defense against fungal infections.Frontiers in nutrition · 2026Review
- The Contribution of Human Antimicrobial Peptides to Fungi.International journal of molecular sciences · 2025Review
- Antifungal Synergy: Mechanistic Insights into the R-1-R Peptide andInternational journal of molecular sciences · 2024Article
- Antimicrobial Peptides with Anti-International journal of molecular sciences · 2022Review
- Antimicrobial Activity of the Peptide LfcinB15 againstJournal of fungi (Basel, Switzerland) · 2021Article
- "Tissue barriers · 2019Review
- Protein-Protein Interactions inFrontiers in microbiology · 2019Review
- Stress-Activated Protein Kinases in Human Fungal Pathogens.Frontiers in cellular and infection microbiology · 2019Review
- Fungal Strategies to Evade the Host Immune Recognition.Journal of fungi (Basel, Switzerland) · 2017Review
- Fungi that Infect Humans.Microbiology spectrum · 2017Review
- Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses.PLoS pathogens · 2017Review
- Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues.PLoS genetics · 2016Article
- Plant Defensins NaD1 and NaD2 Induce Different Stress Response Pathways in Fungi.International journal of molecular sciences · 2016Article
- Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization.Nature medicine · 2015Article
- β-Defensin 1 plays a role in acute mucosal defense against Candida albicans.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- The spectrum of fungi that infects humans.Cold Spring Harbor perspectives in medicine · 2014Review
- Interplay between Candida albicans and the antimicrobial peptide armory.Eukaryotic cell · 2014Review
- Increased oxidative stress tolerance results in general stress tolerance in Candida albicans independently of stress-elicited morphological transitions.Folia microbiologica · 2014Article
- Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins.Cellular and molecular life sciences : CMLS · 2014Review
- Defensins: antifungal lessons from eukaryotes.Frontiers in microbiology · 2014Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Human β-defensins 2 and 3 are small cationic peptides with antimicrobial activity against the fungal pathogen Candida albicans. We found that hog1 and pbs2 mutants were hypersensitive to treatment with these peptides, pointing to a role of the high-osmolarity glycerol (HOG) pathway in the response to defensin-induced cell injury.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.