Evidence map›Paper›PMID 21129153›Full record

ReviewJournal of cellular and molecular medicine2011

Bone regeneration and stem cells.

K Arvidson, B M Abdallah, L A Applegate, N Baldini, E Cenni, E Gomez-Barrena, D Granchi, M Kassem, Y T Konttinen, K Mustafa and 3 more

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01362413 (Validation of Laboratory Test for Predicting Bone Tissue Regeneration in Patient Affected by Aseptic Pseudarthrosis and Treated With Platelet Gel), which is not on this map. Cited by 131 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 1 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01362413 completednot on this map

Validation of Laboratory Test for Predicting Bone Tissue Regeneration in Patient Affected by Aseptic Pseudarthrosis and Treated With Platelet Gel

TypeobservationalSponsorIstituto Ortopedico RizzoliRan2011 to 2014Enrolled20ConditionsNonunion of Fracture [Pseudarthrosis], Site Unspecified
3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 1 synthesis or guideline pooled it, 400 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
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  12. Article
  13. Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  14. Research Progress of Bone Grafting: A Comprehensive Review.International journal of nanomedicine · 2025
    Review
  15. Carbon dots-based drug delivery for bone regeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
  16. Nanomaterial application for protein delivery in bone regeneration therapy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 9 countries.

K ArvidsonDepartment of Clinical Dentistry, Center for Clinical Resarch, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway. kristina.arvidson@iko.uib.no
B M Abdallah
L A Applegate
N Baldini
E Cenni
E Gomez-Barrena
D Granchi
M Kassem
Y T Konttinen
K Mustafa
D P Pioletti
T Sillat
A Finne-Wistrand
Istituto Ortopedico Rizzoli · ITHelsinki University Hospital · FIUniversity Hospital of Lausanne · CHUniversity of Bergen · NOUniversity of Southern Denmark · DKHospital Universitario La Paz · ESKTH Royal Institute of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed.

Indexed as

AnimalsBone RegenerationFracture HealingHumansOsteogenesisStem CellsTissue EngineeringTissue Scaffolds

Identifiers

PMID21129153
PMCPMC3922662
OpenAlexW2161253076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.