Trial reportDevelopmental cognitive neuroscience2011
Enhanced right amygdala activity in adolescents during encoding of positively valenced pictures.
Trial report in Developmental cognitive neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Abnormal amygdala resting-state functional connectivity in adults and adolescents with major depressive disorder: A comparative meta-analysis.EBioMedicine · 2018Pooled it
- Future Time Perspective and Locomotion Jointly Predict Anticipatory Pleasure in Adolescence: An Integrative Hierarchical Model.European journal of investigation in health, psychology and education · 2025Article
- Impacts of early life adversity on the neurocircuitry of emotional memory in children.Development and psychopathology · 2025Article
- How do positive and negative emotions influence children's and adolescents' arithmetic performance?PloS one · 2025Article
- Article
- Effects of stress on 6- and 7-year-old children's emotional memory differs by gender.Journal of experimental child psychology · 2020Article
- It Is All in the Right Amygdala: Increased Synaptic Plasticity and Perineuronal Nets in Male, But Not Female, Juvenile Rat Pups after Exposure to Early-Life Stress.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Impaired left amygdala resting state functional connectivity in subthreshold depression individuals.Scientific reports · 2020Article
- Keeping in Touch with Mental Health: The Orienting Reflex and Behavioral Outcomes from Calatonia.Brain sciences · 2020Review
- Left, right, or bilateral amygdala activation? How effects of smoothing and motion correction on ultra-high field, high-resolution functional magnetic resonance imaging (fMRI) data alter inferences.Neuroscience research · 2020Article
- Aversive learning strengthens episodic memory in both adolescents and adults.Learning & memory (Cold Spring Harbor, N.Y.) · 2019Article
- Emotion effects on memory from childhood through adulthood: Consistent enhancement and adult gender differences.Journal of experimental child psychology · 2019Article
- Amygdala habituation and uncinate fasciculus connectivity in adolescence: A multi-modal approach.NeuroImage · 2018Article
- The transition from childhood to adolescence is marked by a general decrease in amygdala reactivity and an affect-specific ventral-to-dorsal shift in medial prefrontal recruitment.Developmental cognitive neuroscience · 2017Article
- Pruning or tuning? Maturational profiles of face specialization during typical development.Brain and behavior · 2016Article
- Adolescent neurobiological susceptibility to social context.Developmental cognitive neuroscience · 2016Review
- Brain functional correlates of emotion regulation across adolescence and young adulthood.Human brain mapping · 2016Article
- Neurocognitive bases of emotion regulation development in adolescence.Developmental cognitive neuroscience · 2015Review
- Typical and atypical neurodevelopment for face specialization: an FMRI study.Journal of autism and developmental disorders · 2015Article
- Use of the light/dark test for anxiety in adult and adolescent male rats.Behavioural brain research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
While studies among adults implicate the amygdala and interconnecting brain regions in encoding emotional stimuli, few studies have examined whether developmental changes occur within this emotional-memory network during adolescence. The present study examined whether adolescents and adults differentially engaged the amygdala and hippocampus during successful encoding of emotional pictures, with either positive or negative valence. Eighteen adults and twelve adolescents underwent event-related fMRI while encoding emotional pictures. Approximately 30 min later, outside the scanner, subjects were asked to recall the pictures seen during the scan. Age group differences in brain activity in the amygdala and hippocampus during encoding of the pictures that were later successfully and unsuccessfully recalled were separately compared for the positive and negative pictures. Adolescents, relative to adults, demonstrated enhanced activity in the right amygdala during encoding of positive pictures that were later recalled compared to not recalled. There were no age group differences in amygdala or hippocampal activity during successful encoding of negative pictures. The findings of preferential activity within the adolescent right amygdala during successful encoding of positive pictures may have implications for the increased reward and novelty seeking behavior, as well as elevated rates of psychopathology, observed during this distinct developmental period.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.